Pattern of electrolyte abnormalities among cancer patients referred to palliative care: a review of 750 patients

Alsirafy, Samy A.; Al-Shahri, Mohammad Zafir; Hassan, Azza; Hidayatullah, Mohammad; Ghanem, Hafez

doi:10.1179/096992607x196123

Cited by 9 publications

(10 citation statements)

References 25 publications

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“…2,3 In a previous study, 79% of inpatients with cancer referred to palliative care had at least one electrolyte abnormality. 4 While electrolyte abnormalities are common among palliative care patients with cancer, few had been studied for their prognostic value in the palliative care setting. 5 The aim of the current study was to preliminary assess the predictive significance of abnormalities related to five electrolytes on the admission outcome and survival of patients with cancer referred to palliative care service.…”

Section: P Rognostication In Palliative Care Is Increasingly Gain-mentioning

confidence: 99%

Predictive Impact of Electrolyte Abnormalities on the Admission Outcome and Survival of Palliative Care Cancer Referrals

Alsirafy

Sroor

Al-Shahri

2009

Journal of Palliative Medicine

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Section: P Rognostication In Palliative Care Is Increasingly Gain-mentioning

confidence: 99%

Predictive Impact of Electrolyte Abnormalities on the Admission Outcome and Survival of Palliative Care Cancer Referrals

Alsirafy

Sroor

Al-Shahri

2009

Journal of Palliative Medicine

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“…It makes EAD ubiquitous in patients diagnosed with cancer. Previous studies reported the incidence of hyponatremia and hypokalemia in cancer patients was up to 47-64% [4,5] and 41-48% [6,7] respectively. The occurrence of various EAD is concomitant and can trigger a series of symptoms such as delirium, fatigue, constipation, nausea, vomiting, and even the in-hospital death [8,9].…”

Section: Introductionmentioning

confidence: 95%

Electrolyte and acid-base disorders in cancer patients and its impact on clinical outcomes: evidence from a real-world study in China

et al. 2020

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Background: This study aims to delineate the incidence of electrolyte and acid-base disorders (EAD) in cancer patients, to figure out the risk factors of EAD, then to assess the impact of EAD on patients' in-hospital clinical outcomes. Methods: Patients with the diagnosis of malignancies hospitalized during 1 October 2014 and 30 September 2015 were recruited in Zhongshan Hospital, Fudan University in Shanghai of China. Demographic characteristics, comorbidities, and clinical data, including survival, length of stay and hospital cost, were extracted from the electronic medical record system. Electrolyte and acid-base data were acquired from the hospital laboratory database. Results: Of 25,881 cancer patients with electrolyte data, 15,000 (58.0%) cases had at least one electrolyte and acid-base abnormity. Hypocalcemia (27.8%) was the most common electrolyte disorder, followed by hypophosphatemia (26.7%), hypochloremia (24.5%) and hyponatremia (22.5%). The incidence of simple metabolic acidosis (MAC) and metabolic alkalosis (MAL) was 12.8% and 22.1% respectively. Patients with mixed metabolic acid-base disorders (MAC þ MAL) accounted for 30.2%. Lower BMI score, preexisting hypertension and diabetes, renal dysfunction, receiving surgery/chemotherapy, anemia and hypoalbuminemia were screened out as the major risk factors of EAD. In-hospital mortality in patients with EAD was 2.1% as compared to those with normal electrolytes (0.3%). The risk of death significantly increased among patients with severe EAD. Similarly, the length of stay and hospital cost also tripled as the number and grade of EAD increased. Conclusion: EAD is commonly encountered in cancer patients and associated with an ominous prognosis. Patients with comorbidities, renal/liver dysfunction, and anti-tumor therapy have a higher risk of EAD. Regular monitoring of electrolytes, optimum regimen for intravenous infusion, timely correction of modifiable factors and appropriate management of EAD should not be neglected during anti-tumor treatment.

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“…[4] Inadequate noncancer PC is a problem that should be addressed at a national level in Saudi Arabia.…”

Section: Discussionmentioning

confidence: 99%

Pattern of referral of noncancer patients to palliative care in the Eastern province of Saudi Arabia

Ghanem

Shaikh

Alia

et al. 2011

Indian J Palliat Care

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Aim:The palliative care (PC) needs of patients with noncancer life-threatening illnesses are comparable to that of cancer patients. This report describes the contribution of noncancer patients to the population of PC patients in a tertiary care hospital in the Eastern Province of Saudi Arabia.Materials and Methods:This is a retrospective review of the “palliative care inpatient database” of 21 months.Results:From 474 patients, 20 (4.2%) had a noncancer diagnosis. The main reason for the referral of noncancer patients was pain control. The most prevalent diagnoses were sickle cell disease (SCD) in 6 (30%) patients and peripheral arterial disease (PAD) in 5 (25%).Conclusions:These findings suggest that the PC needs of noncancer patients are largely unmet in our region. Further efforts are necessary to advance noncancer PC in Saudi Arabia. The PC needs of patients with SCD and PAD need to be addressed in future research.

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Pattern of electrolyte abnormalities among cancer patients referred to palliative care: a review of 750 patients

Cited by 9 publications

References 25 publications

Predictive Impact of Electrolyte Abnormalities on the Admission Outcome and Survival of Palliative Care Cancer Referrals

Predictive Impact of Electrolyte Abnormalities on the Admission Outcome and Survival of Palliative Care Cancer Referrals

Electrolyte and acid-base disorders in cancer patients and its impact on clinical outcomes: evidence from a real-world study in China

Pattern of referral of noncancer patients to palliative care in the Eastern province of Saudi Arabia

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