Pattern Of Epilepsy In Childhood And Adolescence : A Hospital-Based Study

Kandil,; Ahmed, WM; Sayed, Abida; Hamed, SA

doi:10.4314/ajns.v26i1.7592

Cited by 11 publications

(16 citation statements)

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“…Kandil et al, also observed generalized tonic-clonic seizures as the most common type of seizures and was seen in 72.1% cases. 17 In the present study only 5 (6.6%) cases presented with status epilepticus. Irdo et al, in their study found status epilepticus in 9.1% cases.…”

Section: Generalised Versus Partial Seizurescontrasting

confidence: 49%

“…Kandil et al, and Mwipopo et al, observed a positive family history of seizures in 17.3% and 9.5% of their patients respectively. 16,17 In the present study, 80% of children had presented with first episode of seizures and 20% of children had past history of seizure.…”

Section: Generalised Versus Partial Seizuresmentioning

confidence: 51%

“…16 Kandil et al, reported an almost equal gender ratio for seizures (64 males and 63 females). 17 Prevalence of seizures: Idro et al, in their Kenyan study observed a prevalence of 18.3%. 10 Chaudhary et al, found a prevalence of 3.4% for seizures in Western Nepal.…”

Section: Gender Distributionmentioning

confidence: 99%

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Study of prevalence and clinical spectrum of seizures in children in a teaching hospital in rural Telangana, India

Sastry¹,

Reddy²

2018

Int J Contemp Pediatr

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Background: To study the prevalence and clinical spectrum of seizures and treatment outcome in children.Methods: A hospital based prospective study was done at Maheshwara Medical College and Hospital, Patancheru, Telangana in the department of Paediatrics over one-year period. A total of 75 cases presenting with seizures were studied for demographics, clinical features, imaging studies where possible and patient response to treatment. Results: T Patient age ranged from one week to 14 years with male to female ratio of 1:4. Majority were in the age group of 1-3 years 25/75 (33.3%). Fever was present on admission in 66.6% of cases in 1 month to 6 years. Unprovoked seizure was common 20/75 (26.6%) in age group 6 to14 years. Neonatal seizures were seen in 6.6% cases. Generalized tonic clonic seizures were common and were seen in 63.3% cases. Only 5 (6.6 %) cases presented with status epilepticus. CT scan was done in 20 cases in unprovoked seizures and showed various etiologies. Conclusions: Seizures in children are a common indication for hospital admission. They can be febrile or unprovoked. CNS infections and space occupying lesions are common causes for paediatric seizures. Early detection of the cause of seizures helps in instituting appropriate treatment. Children with unprovoked seizures should be on regular long term follow up and treatment.

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Section: Generalised Versus Partial Seizurescontrasting

confidence: 49%

Section: Generalised Versus Partial Seizuresmentioning

confidence: 51%

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Study of prevalence and clinical spectrum of seizures in children in a teaching hospital in rural Telangana, India

Sastry¹,

Reddy²

2018

Int J Contemp Pediatr

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“…8 Among 20 seizure cases 10(50%) were in the age group below 3 years, 7(35%) were in the age group seen in 72.1% cases. 25 and another study reported out of total (326) seizures, 83(25%) of them were febrile seizures where 52 (62.65%) were male and 31 (37.35%) were female, i.e. male to female ratio is 1.68: 1.…”

Section: Introductionmentioning

confidence: 93%

Childhood seizures: Prevalence and its related factors, associated problems and outcome

Gogoi¹

2019

IJSSR

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Seizures are the most common pediatric neurological disorder worldwide. Four to ten percent of children suffer at least one episode of seizure in the first 16 years of life. The incidence is highest in children less than 3 years of age. It has an impact on many aspects of a child's development and functioning. The aim of the study is to find out the prevalence of childhood seizure and its related factors, associated problems and outcome of seizures in a tertiary hospital, Guwahati, Assam. Cross-sectional study carried out in the Department of Pediatrics Medicine, Guwahati Medical College Hospital among children with presenting seizures. A purposive sampling technique was adopted and information was gathered through interview schedule, observation and medical records. Out of 854 patients 20 (2.34 per 100) children had seizures as a presenting complain. The incidence is highest10 (50%) in children less than 3 years of age, with a decreasing frequency in older children and equal number of male 10(50%) and female 10 (50%) were presenting seizures. Generalized tonic clonic seizures were the commonest type of seizure in this study 19(69.9%) and 17(85%) of them were febrile. The study reported that out of total seizure cases, 17(85%) of cases having history of fever, 15(75%) rhinorrhea, 2(10%) vomiting and headache as an associating factors and majority of 18 (90%) cases had no family history of seizure only 2(10%) reported as having family history of seizure. No mortality rate was found due to seizure. 10 % of cases were leave against medical advice (LAMA) and 90% of cases discharged with recovery. Seizures are the most common pediatric neurological disorder. The incidence is highest in children less than 3 years of age, with a decreasing frequency in older children.

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“…It is higher in developing countries with a prevalence of 10-12 per 1,000. In Egypt, the prevalence rate was estimated to be 8 per 1,000 and in Upper Egypt the prevalence rate was 12.9 per 1,000 (2) . Unfortunately, only 70% of patients are effectively treated with currently available antiepileptic drugs (AEDs) (3) .…”

Section: Introductionmentioning

confidence: 99%

Vitamin C Antioxidant Effects in Brain of Albino Mice after Seizures and Status Epilepticus Induced by Pentylene-tetrazole (PTZ)

Ali

Ewais

Khalil

et al. 2013

Suez Canal University Medical Journal

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Aim: Oxidative stress has been implicated in the neurological diseases, one of them is epilepsy. Therefore, this study was conducted to determine the effect of vitamin C as an acute antioxidant protective treatment of epilepsy in mice. Materials and Methods: Seventy-eight male albino mice were divided into six groups. The first group was a normal control group that received NaCl, 0.9% (i.p.). The second group received PTZ (65 mg/kg, i.p.) as a single convulsive dose. The third and fourth groups received vitamin C (500 mg/kg/day, i.p.) and vitamin C (1000mg/kg, i.p.) respectively. The fifth and sixth groups received vitamin C (500 mg/kg/day, i.p.) and vitamin C (1000 mg/kg, i.p.) respectively, then after 30 minutes both received Pentylenetetrazole (PTZ) (65 mg/kg i.p.) as a single convulsive dose. Behavioral assessment was done immediately after injections using Racine scale and rotarod tests then after 24 hours, the animals were killed and brain tissue homogenates were prepared to measure lipid peroxide (Malondialdehyde) and catalase activity. Results: Vitamin C showed decreased percentage of seizures, prolonged latency to 1 st seizure, improved motor coordination, decreased lipid peroxide level and increased catalase activity. No difference in results between groups received vitamin C (500 mg/kg, i.p.) or (1000 mg/kg, i.p.). Conclusion: Vitamin C was proven to be a potential candidate for decreasing risk of epilepsy.

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Pattern Of Epilepsy In Childhood And Adolescence : A Hospital-Based Study

Cited by 11 publications

References 0 publications

Study of prevalence and clinical spectrum of seizures in children in a teaching hospital in rural Telangana, India

Study of prevalence and clinical spectrum of seizures in children in a teaching hospital in rural Telangana, India

Childhood seizures: Prevalence and its related factors, associated problems and outcome

Vitamin C Antioxidant Effects in Brain of Albino Mice after Seizures and Status Epilepticus Induced by Pentylene-tetrazole (PTZ)

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