Pattern of intracranial tumours in a tertiary hospital in Ghana

Ekpene, Ubong U; Ametefe, Mawuli; Akoto, Henry; Bankah, Patrick; Totimeh, Teddy; Wepeba, George; Dakurah, Thomas

doi:10.4314/gmj.v52i2.3

Cited by 16 publications

(25 citation statements)

References 13 publications

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“…Gliomas were found to be the widespread tumor type, representing 38.2% of intracranial tumors next to meningioma (Howlett, 2018;Olufunsho, et al 2011). Though gliomas are found to be widespread in men population (Howlett, 2018), there was a minor female majority in study by Ekpene, et al (2018), which is close to an earlier publication in Andrews et al (2003). The reason cited was that female population are likely to search for medical treatment more than their opposite counterparts.…”

Section: Discussionsupporting

confidence: 78%

“…The mean age of report of intracranial tumor in relation to gender exhibited that female population represented at a comparatively higher age in the adults, but earlier than men population in the paediatric groups (Ekpene, et al 2018). Headache was found to be the commonest sign as reported in one other study (Howlett, 2008) followed by visual impairment and seizures.…”

Section: Discussionmentioning

confidence: 73%

“…Tagoe, et al (2015) stated that seizure is the most common sign among intracranial tumor patients. Focal neurologic deficit is also found to be one of the commonest symptoms (Ekpene, 2018). Gliomas were found to be the widespread tumor type, representing 38.2% of intracranial tumors next to meningioma (Howlett, 2018;Olufunsho, et al 2011).…”

Section: Discussionmentioning

confidence: 99%

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Intracranial Tumors- Overview, Histological Types, Symptoms and Treatment Plans

Chaulagain

Smolanka

2021

Int J Health Sci Res

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People, in general, are affected by a brain or intracranial tumor when abnormal cells started functioning within their brain. This paper explores mainly tumors that affect the brain. Almost every type of brain tumor might create symptoms which are based on the parts of the brain affected. In order to better understand reasons of occurrence intracranial tumors in various sections of the population, the study examined the relationship between sociodemographic variables, i.e., age, gender and marital status and the relative frequency of intracranial tumors as part of a study. Samples are collected based on the information from Uzhhorod Regional Center of Neurosurgery and Neurology in Ukraine. And factors such as age, gender and marital status has been considered to examine tumor size variation. The ratios of organ cancers in Ukrainians are evidently increasing. Besides, there has been growing trend in affected rates in both the genders of CNS cancers have been noticed in all the records. The ratio of most harmful brain tumors is comparatively in minimal ratio in East and Southeast Asia, and India. On the other hand, the highest ratio has been noted in European countries and as well United States, and Ukraine is one of those countries. The major burdens of cancer frequency in Ukraine have been noticed in the lung, breast, and prostate and brain. Of these, brain tumor rate in Ukraine had been hardly studied. The major difference in frequency in Asian and European populations implies the potential influence of genetic or environmental factors in malignant brain tumors. Continuing monitoring of tumor ratio in Ukraine is essential to comprehend how best to reduce cancer burden globally and to explain the causes of provincial variations, for example access to diagnosis methods and ecological exposures. Key words: Intracranial tumors, symptoms, tumor incidence in Ukraine, treatment plans, survival rate of cancer in Ukraine.

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Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 73%

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Intracranial Tumors- Overview, Histological Types, Symptoms and Treatment Plans

Chaulagain

Smolanka

2021

Int J Health Sci Res

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“…[15][16][17] A study by Ukpene et al at the Korle Bu Teaching Hospital in Accra, Ghana reported meningiomas as 39.3% of primary intracranial tumours but were second to gliomas in frequency of occurrence. [18] The documented percentage ranges from between 15-36% in studies from different parts of the world. [1,[4][5][6][7][8][9][10] The high percentage of meningioma amongst intracranial tumours documented in these studies is supported by a documented higher incidence of meningioma in people of the black race.…”

Section: Discussionmentioning

confidence: 99%

A Retrospective Analysis of Intracranial Meningiomas in a Tertiary Health Care Facility in North Central Nigeria

Akpa¹,

Kwaghe²,

Innocent³

et al. 2021

AJLM

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Introduction/Aim: There is scanty detailed published literature on meningiomas in Nigeria and other parts of Africa. This study is aimed at exploring the demographics, histopathology and presenting symptoms/signs of meningioma in our tertiary health facility and comparing it with other published literature. Methodology: This is a hospital based retrospective study of all histopathologically diagnosed meningioma cases at the department of histopathology of the Jos University Teaching Hospital in plateau state North-Central Nigeria. The period of review is between the 1st of January 2012 to the 31st of December 2020. Materials utilized for this research consisted of Archival histopathology glass slides, paraffin wax tissue blocks, electronic surgical pathology result data base, electronic cancer registry entries and hard copies of patient case files. The age, sex, intracranial location, histomorphological variant, grade and presenting symptom/sign was documented for all cases and analyzed. Results: Thirty-four (34) cases of meningioma out of 87 primary intracranial neoplasms were histopathologically diagnosed over the 9 years of review. There was a female predominance, with a M:F of 1:1.61. The peak age of diagnoses occurred in the 5 th and 6 th decades for females and males respectively. The commonest histomorphological variant was the Meningothelial type with the commonest intracranial site of diagnosis being the convexities. The most frequently occurring presenting symptom/sign were headache, seizures and visual impairment. Conclusion: Meningioma is the commonest intracranial tumour diagnosed at the Jos University teaching Hospital, In North central Nigeria. This tumour occurs at a relatively younger age in our environment. The sex distribution, variants, grades and symptoms/signs of this tumour in our study conforms to what is obtainable in other parts of the world.

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“…The epidemiology of brain tumors varies globally between different countries, with an increased incidence in high income countries (HICs) as compared to LMICs [2]. Also, the epidemiology of brain tumors differs by age and gender as has been shown in the increased occurrence of meningiomas in females than in males and the occurrence of craniopharyngiomas and medulloblastomas in children more than in adults [4,5].…”

Section: Introductionmentioning

confidence: 99%

Clinicopathological Patterns and Surgical Outcomes of Primary Brain Tumors Managed at a Tertiary Hospital in Arusha, Tanzania:a Cross-sectional Analysis.

Magwesela

Msemakweli

Rabiel

2022

Preprint

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Purpose: The epidemiology of brain tumors varies globally between different countries and there is observed poor outcomes in lower- and middle-income countries. Our aim is to analyze the clinicopathological pattern of intracranial tumors in our setting and their post-surgical outcomes.Methods: This is a retrospective study. Data was obtained from clinical records of patients with intracranial tumors treated at our neurosurgery unit between 2019 and 2020. Only patients with primary brain tumors who underwent surgical intervention were included. Analysis was done to identify factors associated with patient outcomes (mortality/survival and performance status).Results: 39 patients with primary brain tumors underwent surgery (adults 72.8%, males 53.8%, mean age 35.8years). Gliomas (46.2%) comprised the most common tumor diagnosis overall and craniopharyngiomas were the most common tumors in pediatric patients (27.3%). Most patients (83.3%) had a poor performance status before surgery. Gross tumor resection (25.6%) was low and few patients (31.4%) underwent adjuvant therapy. 30-day mortality rate (10.3%) and one year mortality rate (46.2%) were high. Pediatric patients had a much worse outcome (46.2% mortality rate compared to 25% in adults, and 80% with poor performance status) as did males (38.1% mortality rate compared to 27.8% in females). Gliomas accounted for majority (69.2%) of the deaths.Conclusion: Delayed presentation and poor access to adjuvant therapies are important contributors of the high mortality and abandonment of treatment. Inadequate long-term follow-up is a hinderance to optimal neurooncological care in our setting.

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Pattern of intracranial tumours in a tertiary hospital in Ghana

Cited by 16 publications

References 13 publications

Intracranial Tumors- Overview, Histological Types, Symptoms and Treatment Plans

Intracranial Tumors- Overview, Histological Types, Symptoms and Treatment Plans

A Retrospective Analysis of Intracranial Meningiomas in a Tertiary Health Care Facility in North Central Nigeria

Clinicopathological Patterns and Surgical Outcomes of Primary Brain Tumors Managed at a Tertiary Hospital in Arusha, Tanzania:a Cross-sectional Analysis.

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