Pattern of Liver Disease Admissions at a Tertiary Government Hospital in Sana’a, Yemen

Abstract

Back ground and objectives: Liver disease causes major public health problems international, especially in poor countries, and it is associated with poor long-term clinical outcomes and results in the deaths of millions worldwide annually. The aim of this study is to ascertain the virtual frequencies of liver disease and to assess etiological factors among patients admitted to Al-Thawra tertiary Hospital in Sana'a City, Yemen. Methods: This was a descriptive retrospective analysis study of gastrointestinal patients admitted from January 1, 2021 to December 31, 2021 to the medical wards of Al-Thawra Hospital. This is a tertiary hospital located in the Yemeni capital, Sana'a City. Data were extracted from patient case folders for the period of under review. Data validated with Microsoft Excel version 13 and exported to SPSS version 23.0 for windows; for statistical analysis. Data were evaluated for demographic and other clinical characteristics as definite variables. Results: Of the 516 gastroenterology patients admitted to the gastroenterology service in medical wards during a one-year period, liver disease accounted for 30% of all gastroenterology in the same period. There were 155 patients diagnosed with liver disease. There were 86 (55.5%) males and 69 (44.5%) females, with a male to female ratio of 1.2:1. The mean overall age of patients and the age range were 46.14±16.5 and 8-85 years, respectively. The peak incidence of age occurred during the fifth and sixth decades of life at 38.1%. The most common liver disease was; autoimmune hepatitis 43 (27.7%), followed by nonalcoholic fatty liver disease 35 (22.6%), viral hepatitis 32 (20.6%) and schistosomiasis 10 (6.5%). Conclusion: Current findings show that autoimmune hepatitis was the most common cause among gastrointestinal diseases in Sana'a city, Yemen; the male to female ratio was roughly the same. In light of this, health education and public awareness about hepatitis virus screening tests and schistosomiasis screening and treatment is the primary preventive strategy to be considered.

Association of Epstein-Barr Virus With Systemic Lupus Erythematosus by Limited Materials: Patient Characteristics and Clinical Manifestations in Yemen

“…Fatigue in SLE is likely to be multifactorial and is not only associated with disease activity, but also with complications such as hypothyroidism or anemia 12 . In recent years, viral infection and autoimmune diseases have been well studied in Yemen, where many studies have been conducted in this aspect [13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31] , but only one previous study discussed SLE in Yemen 12 , and another study discussed the association of EBV with diseases Autoimmune (rheumatoid arthritis) 13 . However, there is no study associated with EBV infection with clinical features and SLE in Yemen and this study is the first to discuss this topic.…”