Pattern of Precipitating Causes of Diabetic Ketoacidosis in A Tertiary Care Hospital of Bangladesh

Rahim, Muhammad Abdur; Rouf, Rozana; Ahmed, Ashraf Uddin; Uddin, Khwaja Nazim; Latif, Zafar Ahmed

doi:10.3329/bjmed.v29i1.35401

Cited by 1 publication

(3 citation statements)

References 11 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is in similar with studies done by Edao A. in Nigerian and Desse Ta and Gizework M in Ethiopian studies documented that poor drug compliance and infections were the main precipitating factors of hyperglycemic emergencies (8, 10,12). This is also consistent with the nding observed among the Bangladesh population in which infection and nonadherence to anti-diabetic therapy were the predominant precipitating factors (7).…”

Section: Discussionsupporting

confidence: 90%

“…The death rate noticed in the current study was better than the nding reported in Thailand, Bangladesh, and Tanzania, in which death accounted for 4.3%, 6.5%, and 24.1% respectively. Similarly, The rate of mortality was far better than the gure (23.6%) reported by Pakistani authors (7,(19)(20)(21)(22).…”

Section: Limitationsmentioning

confidence: 67%

“…Infection is the most frequent factor for the occurrence of DKA according to different studies (7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical Pattern, Precipitating Factors, and Outcome of Diabetic Ketoacidosis Patients Visiting Adult Emergency at Saint Paul’s Hospital Millennium Medical College

Belachew,

Tesfay,

Getachew

et al. 2024

Preprint

View full text Add to dashboard Cite

Introduction: Diabetic ketoacidosis (DKA) is one of the most common acute complications of diabetes mellitus. The mortality rate of DKA was higher in developing countries. Diabetes mellitus has life-threatening complications that are precipitated by various factors such as infections, trauma, cardiovascular diseases, and pregnancy. This study aimed to assess the clinical pattern, precipitating factors, and outcome of DKA. Methodology: A hospital-based cross-sectional study was done at St. Paul’s Hospital Millennium Medical College. Diabetic ketoacidosis patients who were admitted from January 1st, 2019 to December 31st, 2021 were included. The sample size was estimated using the single population proportion formula. Data were analyzed using SPSS version 25. Descriptive analysis and bivariate multiple regression analyses were used. Statistical significance was considered for variables with p < 0.05. Results: A total of 261 medical charts of diabetic patients with DKA were analyzed. Patients’ median (interquartile range) age was 35 (26–46) years, with male predominance (62.1%). Polydipsia and polyuria were the most frequent presenting symptoms. About 39.1% of diabetes was a first-time presentation with DKA while infection and insulin discontinuation were the most common precipitating factors. Sixty-four (24.5%) of the patients had bad management outcomes, with a mortality rate of 1.5%. Having moderate and severe DKA (95% CI: (2.51, 11.62)] and having a lower GCS score at presentation [AOR=3.49 (95%CI: (1.11, 10.99)] were significantly associated with poor management outcome. Conclusion: Polydipsia and polyuria were the most frequent presenting symptoms. One-fourth of DKA patients had poor management outcomes. The due focus should be given to raising the general public’s awareness about precipitating factors and overall comprehensive diabetic care.

show abstract

Section: Discussionsupporting

confidence: 90%