Pattern of Primary Glomerulonephritis in Dhaka Medical College Hospital, Bangladesh

Abstract

Abstract

Histopathological Pattern of Glomerulonephritis: Experience from BIRDEM General Hospital, Dhaka, Bangladesh

“…Other findings with low incidence of IgM nephropathy and pauciimmune GN matches with other studies 10,13 like in Pakistanwhere the incidence of IgM nephropathy was 2.47%. 38 Most of the studies did not mention IgM nephropathy as a distinct category.…”

“…Mundi I et al 10 found most of the cases were in 21-40 age range and distinct pattern of PGN was found in different age ranges. The age range of our cases was 14-72 years with a slight male predominance (1.2:1) except in case of LN and MesPGN.…”

“…In our study though many of our cases were diabetic but there average body built and life style do not yet match with that of the affluent society. Apart from this FSGS has been found to have a racial predilection 10 .Meckenzie etel, 37 have suggested that genetic variation may play a role in sporadic FSGS in adult. These hypothesis also fits with our findings of FSGS but the reason of low incidence of MN could not be explained.…”

“…Mundi I etal and Mannan R et al 10,13 demonstrated FSGS, MN and minimal change disease(MCD) being the commonest form of PGN in India. Data from Singapore and other countries also showed that the prevalence of FSGS and MN have become increased in recent time 1 This may be related to increasing number of patients with obesity, DM and smoking habits, a pattern representing the rising affluence in these countries where FSGS represents the changing life style of fast food and unhealthy diets predisposing to disease like obesity and DM.…”

“…14,33,34 The most likely reason of getting more DN is, BIRDEM is a specialized hospital of diabetis and endocrine diseases and also because other centers usually did not biopsy diabetic patients 16 or did if the diagnosis was doubtful. 10,31 LN is the second common form of secondary GN in our study. Class iv LN is the commonest followed by class v LN which correlates with the finding of Habib MA 14 from Bangladesh.…”