Pattern of psoriasis in a tertiary care teaching hospital in South India

Asokan, Neelakandhan; Prathap, Priya; Ajithkumar, Kidangazhiathmana; Ambooken, Betsy; Binesh, VG

doi:10.4103/0019-5154.77575

Cited by 5 publications

(9 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The inverse psoriasis was the least common (0.9%). Similar observations were found by other authors who reported maximum cases of psoriasis vulgaris (≥ 85%) and almost similar number of cases of erythrodermic psoriasis (2-3%) and inverse psoriasis (1-2%) [12][13][14][15]. Thomas J et al reported higher incidence of palmoplantar psoriasis followed by palmoplantar psoriasis constituting 45% cases and 44% cases of psoriasis vulgaris [16].…”

Section: Discussionsupporting

confidence: 86%

The spectrum of histomorphological features in psoriasis: a three years study

Arora

Mittal

Ahmad

et al. 2019

Trop J Pathol Microbiol

View full text Add to dashboard Cite

Introduction: Psoriasis is a common relapsing chronic inflammatory dermatological disease associated with significant morbidity. Psoriasis is the prototype of a group of cutaneous disorders (psoriasiform dermatitides). Although histopathology is considered 'gold standard' for the diagnosis of psoriasis, at times even histopathological findings are confusing and inconclusive. Aim of the study: To study the histopathological findings at different stages of psoriasis and its subtypes. Materials and Methods: A total of 101 cases were studied for histopathological features. Results: Most of the cases were noted in the age group of 31 to 40 years (25.9%). There was a male predominance with male to female ratio of 2.7:1. Psoriasis vulgaris was the most common clinical type followed by Palmoplantar psoriasisand Erythrodermic psoriasis. Parakeratosis was the only consistent feature followed by ddilated blood vessels/abnormal capillary pattern and elongation of rete ridges with thickening at lower ends. The other frequent features were acanthosis and agranulosis / hypogranulosis. Conclusion: Histopathology of psoriatic plaques exhibits heterogeneity and microscopic features will vary according to the stage of the disease. Though most of the predominant morphologic features of psoriasis are related to the epidermis, the presence of dilated blood vessels and/or abnormal capillary pattern is a constant finding in all stages of psoriasis and thus, can help in diagnosis of psoriatic lesion when in doubt.

show abstract

Section: Discussionsupporting

confidence: 86%

The spectrum of histomorphological features in psoriasis: a three years study

Arora

Mittal

Ahmad

et al. 2019

Trop J Pathol Microbiol

View full text Add to dashboard Cite

show abstract

“…We found only six studies, mostly in a hospital setting, from North India estimating the prevalence of disease among adult dermatologic patients [Table 1]. [345678] A higher prevalence in males has been reported with a peak age at onset is in the third and fourth decade of life. [910] In one of the larger studies from Northern India, point prevalence of pediatric psoriasis was estimated to be 0.0002%.…”

Section: Introductionmentioning

confidence: 99%

Psoriasis: Epidemiology, clinical features, co-morbidities, and clinical scoring

Dogra

Mahajan

2016

Indian Dermatol Online J

View full text Add to dashboard Cite

On the basis of current evidence derived from hospital-based studies, mostly from North India, the prevalence of psoriasis in adults varies from 0.44 to 2.8%, with a much lower prevalence in children. The peak age at onset in adults is in the third and fourth decade of life, with a slight male preponderance. It is recommended that population-based large epidemiologic studies should be undertaken in different parts of the country for estimating the correct prevalence of psoriasis in general population. Chronic plaque-type psoriasis is the most common morphologic presentation of psoriasis, accounting for more than 90% of all cases. Other morphologic variants that deserve special mention include palmoplantar psoriasis, pustular psoriasis, and recalcitrant psoriasis. For epidemiologic purposes, psoriasis can be classified into early and late onset psoriasis. Psoriasis can be classified on the basis of morphology and extent of involvement into localized and widespread disease. For the purpose of clinical trials, psoriasis may be classified as mild psoriasis, moderate psoriasis, and severe psoriasis. The literature shows that there is a significant risk of psoriatic arthritis (7–48%) in patients with plaque-type psoriasis. Hence, it is recommended to evaluate for its presence by detailed history taking and clinical examination, and if necessary, by appropriate radiological investigations. Evidence on the association between plaque-type psoriasis and cardiovascular disease risk factors and ischemic heart disease isinconsistent. On the basis ofavailable evidence, it is prudent to proactively look for metabolic syndrome, dyslipidemia, and obesity, especially in patientswith severe psoriasis (Level 1+ evidence based on systematic reviews and meta-analysis). Based on the current evidence, the psoriasis area severity index appears to be the most valid and reproducible clinical severity score in the management of adult patients with plaque-type psoriasis.

show abstract

“…Similar male preponderance in psoriasis has been reported in other studies too. 3,5,[8][9][10][11][12] Mean age of onset in females (31.7 years) was less than in males (39.6 years). Younger mean age at onset among females was also noted in other studies.…”

Section: Discussionmentioning

confidence: 99%

“…Many studies are available in the literature outlining epidemiological and clinical pattern of psoriasis in different regions of India. [3][4][5][6][7][8][9][10][11] However, comprehensive data on prevalence and pattern of psoriasis in Uttarakhand, a state of India, which came into being in year 2000, is lacking. It was, therefore, planned to study the prevalence and pattern of the psoriasis in patients attending Dermatology Outpatient Department (OPD) of Himalayan Institute of Medical Sciences, Dehradun, a major tertiary care centre and teaching hospital situated in the foothills of Garhwal Himalayas, in Uttarakhand.…”

Section: Introductionmentioning

confidence: 99%

Psoriasis- A Clinical Study From Garhwal Region of Uttarakhand

Rawat¹,

Bhardwaj²,

Jain³

2017

jebmh

View full text Add to dashboard Cite

BACKGROUND Psoriasis is a chronic, genetically determined, inflammatory, immune-mediated skin disease. Its prevalence and pattern are influenced by diverse genetic, ethnic and environmental factors. Many epidemiological studies of prevalence and pattern of psoriasis are available from different parts of India. Comprehensive data on its prevalence and patterns in Uttarakhand State, however, is lacking. The aim of the study is to study prevalence and pattern of psoriasis at a tertiary referral hospital in Garhwal region of Uttarakhand. MATERIALS AND METHODS This was a retrospective study in which clinical data of all patients of psoriasis who attended psoriasis clinic in outpatients Department of Dermatology, between October 01, 2012, to September 30, 2015, were analysed. A total of 1197 patients formed the study subjects. Diagnosis was clinical in most of the cases. RESULTS Out of a total 46,044 patients seen in outpatients Department of Dermatology during study period, 1197 patients were of psoriasis constituting 2.6% of all skin OPD patients. Male-to-female ratio was 2.4:1. The mean age of onset in males was 39.6 years as against 31.7 years in females. Seasonal variation was seen in 64.5% cases with winter aggravation in 49% cases. Chronic plaque type psoriasis (88%) was commonest morphological type. Arthritis was seen in 7.3% cases. Pustular and erythrodermic psoriasis accounted for less than 1% cases each. CONCLUSION Psoriasis is a common dermatological disease in Garhwal region of Uttarakhand accounting for 2.6% of all skin OPD patients. The pattern and epidemiological characteristics of the disease are same as in other regions of India.

show abstract

Pattern of psoriasis in a tertiary care teaching hospital in South India

Cited by 5 publications

References 1 publication

The spectrum of histomorphological features in psoriasis: a three years study

The spectrum of histomorphological features in psoriasis: a three years study

Psoriasis: Epidemiology, clinical features, co-morbidities, and clinical scoring

Psoriasis- A Clinical Study From Garhwal Region of Uttarakhand

Contact Info

Product

Resources

About