Patterning mechanisms in the evolution of derived developmental life histories: the role of Wnt signaling in axis formation of the direct-developing sea urchin Heliocidaris erythrogramma

Kauffman, Jeffrey S.; Raff, Rudolf A.

doi:10.1007/s00427-003-0365-1

Cited by 28 publications

(15 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…gene regulatory networks [GRNs]) and tools should be transposed to a lecithotrophic species for a comparison of the developmental process and the potential buffering system. One factor that should be considered in any future analysis is the role played by changes in the temporal expression profile of GRNs or their individual components, known to occur in direct developers (Kauffman and Raff, 2003) and the sharing of GRNs between adults and larval stages. For example, heat shock proteins (HSPs) are known to play a number of critical regulatory roles in both development and organismal cellular responses to a variety of environmental stressors.…”

Section: Evolutionary Consequencesmentioning

confidence: 99%

Near future ocean acidification increases growth rate of the lecithotrophic larvae and juveniles of the sea star Crossaster papposus

2010

View full text Add to dashboard Cite

Ocean acidification (OA) is believed to be a major threat for near-future marine ecosystems, and that the most sensitive organisms will be calcifying organisms and the free-living larval stages produced by most benthic marine species. In this respect, echinoderms are one of the taxa most at risk. Earlier research on the impact of near-future OA on echinoderm larval stages showed negative effects, such as a decreased growth rate, increased mortality, and developmental abnormalities. However, all the long-term studies were performed on planktotrophic larvae while alternative life-history strategies, such as nonfeeding lecithotrophy, were largely ignored. Here, we show that lecithotrophic echinoderm larvae and juveniles are positively impacted by ocean acidification. When cultured at low pH, larvae and juveniles of the sea star Crossaster papposus grow faster with no visible affects on survival or skeletogenesis. This suggests that in future oceans, lecithotrophic species may be better adapted to deal with the threat of OA compared with planktotrophic ones with potentially important consequences at the ecosystem level. For example, an increase in populations of the top predator C. papposus will likely have huge consequences for community structure. Our results also highlight the importance of taking varying life-history strategies into account when assessing the impacts of climate change, an approach that also provides insight into understanding the evolution of life-history strategies.

show abstract

Section: Evolutionary Consequencesmentioning

confidence: 99%

Near future ocean acidification increases growth rate of the lecithotrophic larvae and juveniles of the sea star Crossaster papposus

2010

View full text Add to dashboard Cite

show abstract

“…However, the mechanisms that execute axial differentiation once development has begun are apparently conserved. The A-V axis in H. erythrogramma uses the same Wnt-8 signal transduction pathway as observed in indirect development (Angerer and Angerer, 2003;Kauffman and Raff, 2003). The D-V and L-R axes are established in indirect developers through the upstream action of the Nodal pathway, and the downstream transcription factor goosecoid (gsc) (Angerer et al, 2001;Duboc et al, 2004Duboc et al, , 2005Flowers et al, 2004).…”

Section: Ra Raff and M Byrnementioning

confidence: 99%

The active evolutionary lives of echinoderm larvae

2006

View full text Add to dashboard Cite

Echinoderms represent a researchable subset of a dynamic larval evolutionary cosmos. Evolution of echinoderm larvae has taken place over widely varying time scales from the origins of larvae of living classes in the early Palaeozoic, approximately 500 million years ago, to recent, rapid and large-scale changes that have occurred within living genera within a span of less than a million years to a few million years. It is these recent evolutionary events that offer a window into processes of larval evolution operating at a micro-evolutionary level of evolution of discrete developmental mechanisms. We review the evolution of the diverse larval forms of living echinoderms to outline the origins of echinoderm larval forms, their diversity among living echinoderms, molecular clocks and rates of larval evolution, and finally current studies on the roles of developmental regulatory mechanisms in the rapid and radical evolutionary changes observed between closely related congeneric species.

show abstract

“…On the molecular level, Wnt/␤-catenin signaling and the inhibition of bone morphogenetic protein (BMP) signaling by secreted antagonist such as Chordin and Noggin play a pivotal role in the establishment of the Spemann-Mangold organizer in Xenopus and the shield in zebrafish (4,9,10) as well as in the establishment of axial polarity in the mouse and sea urchin embryo (11)(12)(13)(14)(15). Several of these conserved genes have been described in cnidarians, i.e., members of the Wnt/␤-catenin signaling pathway (16), and their expression pattern is consistent with a function in the Hydra head organizer.…”

mentioning

confidence: 99%

An ancient chordin-like gene in organizer formation of Hydra

Rentzsch

Guder²,

Vocke³

et al. 2007

Proc. Natl. Acad. Sci. U.S.A.

View full text Add to dashboard Cite

Signaling centers or organizers play a key role in axial patterning processes in animal embryogenesis. The function of most vertebrate organizers involves the activity of secreted antagonists of bone morphogenetic proteins (BMPs) such as Chordin or Noggin. Although BMP homologs have been isolated from many phyla, the evolutionary origin of the antagonistic BMP/Chordin system in organizer signaling is presently unknown. Here we describe a Chordin-like molecule (HyChdl) from Hydra that inhibits BMP activity in zebrafish embryos and acts in Hydra axis formation when new head organizers are formed during budding and regeneration. hychdl transcripts are also up-regulated in the head regeneration-deficient mutant strain reg-16. Accordingly, HyChdl has a function in organizer formation, but not in head differentiation. Our data indicate that the BMP/Chordin antagonism is a basic property of metazoan signaling centers that was invented in early metazoan evolution to set up axial polarity.axis formation ͉ bone morphogenetic protein/Chordin ͉ Cnidaria ͉ regeneration ͉ signaling L ocalized signaling centers or organizers are widely used for the patterning of embryos or tissues during animal development. In general, organizers are able to generate polarity in surrounding tissue and to induce specific cell fates and cell behavior (1). One of the best-characterized examples is the amphibian embryonic organizer known as the Spemann-Mangold organizer (2). This organizer, localized at the dorsal blastopore lip, is able to induce the formation of a second body axis upon transplantation to the ventral side of a host embryo. The inductive capacity of the organizer is demonstrated by its ability to recruit host tissue into the second axis (3, 4). Functionally equivalent embryonic organizers are found in most vertebrates, including the node in amniotes and the embryonic shield in teleosts (5). The evolutionary origin of the embryonic organizer is unclear at present, but it was proposed that it is a vertebrate-specific invention (6).There is evidence that the embryonic organizer is much older than commonly assumed. In the freshwater polyp Hydra, a member of the Ͼ500-million-year-old phylum Cnidaria, Browne (7) demonstrated the existence of an organizer-like activity already in 1909: Transplantation of a hypostome into the body column of a labeled host led to the formation of a second body axis including hostderived tissue (7,8). The hypostome is the oral end of a cnidarian body axis and corresponds to the blastopore of a gastrula. However, whether the head organizer of Hydra represents the evolutionary origin of the vertebrate embryonic organizer or whether they arose independently is currently not known.On the molecular level, Wnt/␤-catenin signaling and the inhibition of bone morphogenetic protein (BMP) signaling by secreted antagonist such as Chordin and Noggin play a pivotal role in the establishment of the Spemann-Mangold organizer in Xenopus and the shield in zebrafish (4, 9, 10) as well as in the establishment of axial polarity...

show abstract

Patterning mechanisms in the evolution of derived developmental life histories: the role of Wnt signaling in axis formation of the direct-developing sea urchin Heliocidaris erythrogramma

Cited by 28 publications

References 45 publications

Near future ocean acidification increases growth rate of the lecithotrophic larvae and juveniles of the sea star Crossaster papposus

Near future ocean acidification increases growth rate of the lecithotrophic larvae and juveniles of the sea star Crossaster papposus

The active evolutionary lives of echinoderm larvae

An ancient chordin-like gene in organizer formation of Hydra

Contact Info

Product

Resources

About