Patterns and correlates of non-fatal heroin overdose at 11-year follow-up: Findings from the Australian Treatment Outcome Study

Darke, Shane; Marel, Christina; Mills, Katherine L.; Ross, Joanne; Slade, Timothy; Burns, Lucy; Teesson, Maree

doi:10.1016/j.drugalcdep.2014.09.001

Cited by 38 publications

(23 citation statements)

References 39 publications

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“…The major demographic characteristics, however, were typical of other studies of IDU fatalities nationally and internationally . Importantly, they were also typical of cohorts of living IDU . Moreover, the observed pathologies were consistent with those known to be associated with foreign body embolization.…”

Section: Discussionsupporting

confidence: 71%

The health consequences of injecting tablet preparations: foreign body pulmonary embolization and pulmonary hypertension among deceased injecting drug users

2015

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Section: Discussionsupporting

confidence: 71%

The health consequences of injecting tablet preparations: foreign body pulmonary embolization and pulmonary hypertension among deceased injecting drug users

2015

Self Cite

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“…9,10 Psychiatric risk factors associated with OD in substance users include depression 11 and increased impulsivity. 12 Likewise, a history of a suicide attempt has also been associated with history of OD in substance users 5,13,14 although many of the studies that examined this relationship did not evaluate for differences related to the intentionality of the OD.…”

Section: Introductionmentioning

confidence: 99%

Risk Factors for Overdose in Treatment-Seeking Youth With Substance Use Disorders

Yule¹,

Carrellas²,

Fitzgerald³

et al. 2018

J. Clin. Psychiatry

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Objective Overdoses (OD) are among the leading causes of death in youth with substance use disorders (SUDs). We aimed to identify the prevalence of OD and characteristics associated with a history of OD in youth presenting for SUD outpatient care. Methods Systematic retrospective medical record review of consecutive psychiatric and SUD evaluations for patients age 16 to 26 years at entry into an outpatient SUD treatment program for youth. Unintentional OD was defined as substance use without intention of self-harm that was associated with a significant impairment in level of consciousness. Intentional OD was defined as ingestion of a substance that was reported as a suicide attempt. T-tests, Pearson’s chi-square, and Fisher’s exact tests were performed to evaluate characteristics associated with a history of OD. Results We examined the medical records of 200 patients (157 males and 43 females) with mean age 20.2 (±) 2.8 years. At intake 58 patients (29%) had a history of OD and 62% of those patients had a history of unintentional OD only (n=36). Youth with ≥2 SUDs were 3 times more likely to have a history of OD compared to youth with 1 SUD (all p<0.05). Compared to those without a history of OD those with an OD were more likely to be female and have lifetime histories of: alcohol, cocaine, amphetamine, anxiety, depressive, and/or eating disorders (all p<0.05). Conclusion High rates of OD exist in treatment-seeking youth with SUD. OD was associated with more SUD and psychiatric co-morbidity.

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“…The observation that PO residue injectors were more likely to have overdosed than other participants suggests that they not only have more severe opioid dependency but also have more intense drug use patterns (Darke et al, 2014). In our sample, overdoses may have been caused by the use of several drugs, and not only opioids, since study participants were polysubstance users (minimally cocaine and POs).…”

Section: Discussionmentioning

confidence: 75%

Prevalence and correlates of prescription opioid residue injection

Roy

Arruda

Bertrand

et al. 2016

Drug and Alcohol Dependence

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Background: There is growing evidence of intravenous administration of prescription opioids (POs) in several countries. Preparation of POs for injection may leave residues in containers and filters used by people who inject drugs and may lead to adverse health outcomes if they are injected.Methods: This exploratory study used cross-sectional data from the COSMO study, a prospective cohort of out-of-treatment cocaine users carried out in Montréal (Canada) between October 2010 and August 2015. For this analysis, only one visit per participant was selected, that is, the first time the participant reported PO injection during the study.The outcome of interest, "injection of PO residues", was defined as having injected PO residues from a filter and/or a container in the last month. Correlates of this outcome were identified using logistic regression analyses.Results: Of the 122 participants who reported PO injection during the study period, 41.8% had injected PO residues. Reporting an unstable source of income (AOR=4.26; 95% CI: 1.03-17.69), a recent overdose (AOR=5.45; 95% CI: 1.50-19.88) and a preponderant use of opiates (mostly opiate use versus other drugs excluding alcohol and cannabis) (AOR=2.46; 95% CI: 1.08-5.63) increased the risk of PO residue injection. The odds of reporting PO residue injection rose by 7% per unit increase in the score of psychological distress (AOR=1.07 per unit increase; 95% CI: 1.01-1.12). Conclusions:The findings of this study suggest that PO residue injection is associated with markers of vulnerability. Further investigation is needed in order to better understand this understudied drug injection practice.

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Patterns and correlates of non-fatal heroin overdose at 11-year follow-up: Findings from the Australian Treatment Outcome Study

Cited by 38 publications

References 39 publications

The health consequences of injecting tablet preparations: foreign body pulmonary embolization and pulmonary hypertension among deceased injecting drug users

The health consequences of injecting tablet preparations: foreign body pulmonary embolization and pulmonary hypertension among deceased injecting drug users

Risk Factors for Overdose in Treatment-Seeking Youth With Substance Use Disorders

Prevalence and correlates of prescription opioid residue injection

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