Patterns and Outcome of Autoimmune Chronic Liver Diseases in Assiut University Hospital: A Retrospective Study

Abstract

Background& aim: Autoimmune liver diseases (AILD) are relatively low diseases but their pattern and outcome are still unclear. It includes primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH). The current study was conducted to assess pattern of AILDs in our locality Methods: This retrospective study was conducted between 2016 and 2019 in Tropical Medicine and Gastroenterology Department, Assiut University Hospitals. In addition to characteristics of patients, types and outcome of AILDs were registered. Results: A total of 1750 patients with various chronic liver diseases were identified only 2.9% of those patients had different types of AILDs, as follows: 40 patients had AIH, 6 patients had PSC, and 4 patients had PBC, 80% of them were females. Conclusion: AILDs are still underappreciated in our community. Patients with unexplained abnormalities in liver functions should be suspected of having such diseases. Future multi-center studies on this topic are necessary.