Patterns and utility of myelin oligodendrocyte glycoprotein (MOG) antibody testing in cerebrospinal fluid

Burton, Jodie M.; Youn, Saerom; Al-Ani, Abdullah; Costello, Fiona

doi:10.1007/s00415-024-12213-7

J Neurol

2024

DOI: 10.1007/s00415-024-12213-7

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Patterns and utility of myelin oligodendrocyte glycoprotein (MOG) antibody testing in cerebrospinal fluid

Jodie M. Burton,

Saerom Youn,

Abdullah Al-Ani

et al.

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2024

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Cited by 2 publications

References 17 publications

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Optical coherence tomography: implications for neurology

Al-Ani,

Benard-Seguin,

Costello

2024

Current Opinion in Neurology

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Purpose of review This article explores the role of optical coherence tomography (OCT) in neurology practice, particularly in diagnosing and monitoring conditions such as papilledema, optic neuritis, and retinal artery occlusion. OCT has been increasingly utilized as a noninvasive and effective tool for detecting and monitoring neuroaxonal damage in the visual pathway, which is important for early intervention and improved patient outcomes across a variety of neurologic conditions. Recent findings OCT as an imaging modality continues to demonstrate its utility in quantifying optic nerve and retinal changes reflecting neuroaxonal injury, including, peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell layer thickness (or volume). This review focuses on recent evidence regarding the utilization of this modality in diagnosing, monitoring, and quantifying treatment responses in patients with papilledema, optic neuritis, and retinal artery occlusion. Advances in OCT technology, including deep learning algorithms, continue to enhance the diagnostic accuracy and predictive capabilities in the field of neuro-ophthalmology. Summary In recent years, OCT has become an essential tool in neuro-ophthalmic assessment, offering precise structural and anatomical assessments that support diagnosis, treatment planning, and monitoring of conditions affecting the visual pathway. Ongoing advances in OCT technology are expected to further enhance its clinical utility.

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Optical coherence tomography: implications for neurology

Al-Ani,

Benard-Seguin,

Costello

2024

Current Opinion in Neurology

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Optic Neuritis – The Evolving Spectrum

Al-Ani,

Costello

2024

Annals of Indian Academy of Neurology

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Optic neuritis (ON) is an inflammatory condition that affects the optic nerve and may be associated with various central nervous system demyelinating conditions, infectious diseases, and systemic autoimmune syndromes. This manuscript sheds light on the epidemiologic patterns and diverse clinical features of ON, emphasizing the importance of early detection and prompt treatment. Various studies have revealed geographic and ethnic variations across ON subtypes, which are likely related to the incidence and prevalence of co-associated disorders. Distinguishing ON subtypes may be challenging and requires use of paraclinical tools. Treatment strategies differ depending on the etiology, further highlighting the importance of accurately identifying specific ON subtypes in a timely manner.

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Patterns and utility of myelin oligodendrocyte glycoprotein (MOG) antibody testing in cerebrospinal fluid

Cited by 2 publications

References 17 publications

Optical coherence tomography: implications for neurology

Optical coherence tomography: implications for neurology

Optic Neuritis – The Evolving Spectrum

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