“…Some of the common psychoactive polydrugs used include stimulants, opioids, depressants and hallucinogens (UNODC, 2019d; Drug policy network, 2017; Ministry of Health[MoH], 2017). The study byRadcliffe et al (2019) reported that MAT patients had used various polydrug namely; heroin, cocaine, Amphetamine, methamphetamines, hallucinogens, benzodiazepines, novel psychoactive drugs or NPS and cannabis in the past 30 days. The common routes of administration included swallowing, snorting smoking, inhaling fumes, intramuscular injection, subcutaneous injection, intravenous injection, tropical and sublingual, among others…”