Patterns of antimicrobial resistance in a surgical intensive care unit of a university hospital in Turkey

Bayram, Ayşen; Balcı, İclal

doi:10.1186/1471-2334-6-155

Cited by 39 publications

(62 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Consistent with other studies, 6 aspiration pneumonia (49%), pneumonia (10%) and UTI (20%) respectively were the leading form of infection in the subjects of our study. The types of organisms that have emerged as most problematic for patients within the ICU include Acinetobacter spp, Klebsiella spp, Pseudomonas spp, Escherichia coli.…”

Section: Discussionsupporting

confidence: 81%

“…The types of organisms that have emerged as most problematic for patients within the ICU include Acinetobacter spp, Klebsiella spp, Pseudomonas spp, Escherichia coli. 6 In our study, the most frequent microorganisms derived from samples were Acinetobacter spp (29%), Klebsiella spp (26%) and Pseudomonas spp (18%), Escherichia coli (15%) respectively which consistent with other study. In recent years Acinetobacter spp.…”

Section: Discussionsupporting

confidence: 80%

See 1 more Smart Citation

Patterns of Antimicrobial Resistance Among Intensive Care Unit Patients of A Private Medical College Hospital in Dhaka

Islam

Siddiqui²,

Raz³

et al. 2015

Bangla J Med

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 81%

Section: Discussionsupporting

confidence: 80%

Patterns of Antimicrobial Resistance Among Intensive Care Unit Patients of A Private Medical College Hospital in Dhaka

Islam

Siddiqui²,

Raz³

et al. 2015

Bangla J Med

View full text Add to dashboard Cite

show abstract

“…This rate is higher than those reported from Canada (CAN-ICU study) (22.3%) (Zhanel et al, (Fridkin, 2001), and the USA (55%) (Styers et al, 2006), but it is comparable with the report from Turkey (82%) (Bayram, Balci, 2006). Also, the rate of MRSA in the current study is lower than that report separately from Iran (96.2%) (Mohammadtaheri et al, 2010).…”

Section: Discussioncontrasting

confidence: 57%

“…However, this pattern in developing countries such as Brazil (Mendes et al, 2005), Turkey (Kucukates, 2005), Iran (Mohammadtaheri et al, 2010), and other Middle Eastern countries were documented as Pseudomonas and Acinetobacter (Aly, Al-Mousa, Al Asar, 2008;Bayram, Balci, 2006). In the present study, Enterobacter aerogenes followed by E. coli and P. aeruginosa were the organisms most frequently recovered from ICUs.…”

Section: Discussionmentioning

confidence: 72%

Antimicrobial susceptibility patterns among bacteria isolated from intensive care units of the largest teaching hospital at the northwest of Iran

Hamishehkar

Shadmehr

Mahmoodpoor

et al. 2016

Braz. J. Pharm. Sci.

View full text Add to dashboard Cite

This study was conducted to determine the antimicrobial susceptibility patterns among common pathogens in the intensive care units (ICUs) of a university hospital in northwestern Iran. A retrospective study was done on laboratory records of patients with nosocomial infection who were admitted to five ICUs of Imam Reza Hospital during a 21-month period from March 2010 to January, 2012. A total number of 556 isolates from 328 patients were evaluated. The most common sites of infections included respiratory (51.7%), urinary (24.8%), and blood (10.4%). The most frequently isolated microorganisms were Enterobacter aerogenes (50.6%) followed by Escherichia coli (16.7%) and Pseudomonas aeruginosa (7.5%). Staphylococcus aureus was the most frequent pathogen among gram-positives (39.7%). The rate of methicillin-resistant Staphylococcus aureus (MRSA) was 87.5%. Multidrug-resistant (MDR) gram-negative bacteria were documented in 25.8% of Acinetobacter, 20% of Klebsiella, and 16.6% of Pseudomonas. The most active antimicrobials were vancomycin (93.5%) followed by amikacin (71.5%) and gentamicin (46%). The overall antibiotic susceptibility was as follows: 36% ciprofloxacin, 19% imipenem, 20% trimethoprim-sulfamethoxazole, 20.5% ceftazidime, and 12% ceftriaxone. Due to the high rate of antimicrobial resistance in the ICU setting, more surveillance and control of the use of antimicrobials is needed to combat infections. Uniterms:Intensive care units/anti-infective agents/cross infection. Hospital University/Iran. INTRODUCTION Patients a d m i t t e d t o intensive care units (ICUs)are more vulnerable to various nosocomial infections because of their underlying illnesses and exposure to various invasive medical devices (Jatin, Mary, 2012;Archibald et al., 1997;Fridkin, 2001;Kollef, Fraser, 2001;Rhomberg et al., 2006).Hospital infections affect approximately two million patients annually and lead to 90,000 deaths and a cost of $4.5 to $5.7 billion according to reports from the United States (Weinstein, 1998;Jarvis, 2001). They involve 5-10% of ICU patients (CDC, 1992;Stone, Larson, Kawar, 2002).Antibiotics are the mainstay tools in the management of infections. Disappointingly, a number of studies have reported inappropriate uses of antimicrobials as well as the emergence of antibiotic resistance in most parts of the world (Tunger et al., 2009; Bergman et al., 2006). Today, the emergence of multidrug-resistant (MDR) gramnegative and methicillin-resistant Staphylococcus aureus (MRSA) pathogens has become a major public health concern. Moreover, they negatively influence patients' outcomes and increase the length of hospital stays and healthcare costs (Giske et al., 2008;De Kraker et al., 2011;Resch, Wilke, Fink, 2009;Mulvey, Simor, 2009).Many studies have also showed that controlled use of antibiotics leads to improved microorganism sensitivity H. Hamishehkar, P. Shadmehr, A. Mahmoodpoor, S. O. Mashayekhi, T. Entezari-Maleki 404 to antimicrobial agents (Lee et al., 2010;Takesue et al., 2010). The emergence of resistant pathogens ...

show abstract

“…Antimicrobial resistance is generally increasing all over the world, but variations do exist among different countries, probably due to various antimicrobial patterns [13]. A number of factors contribute to this, including the severity of patient illness, predisposition to nosocomial infections, cross-transmission of pathogens characteristic of ward areas within the hospital, and the widespread use of prophylactic and therapeutic anti-infective agents.…”

Section: Discussionmentioning

confidence: 99%

Bacterial pericarditis and antimicrobial resistance at the Tehran Heart Center, Iran

Anvari

Kianinejad

Boroumand

et al. 2015

J Infect Dev Ctries

View full text Add to dashboard Cite

Introduction: When bacterial pericarditis is suspected, urgent pericardial drainage combined with intravenous antibacterial therapy is mandatory to avert devastating, life-threatening complications. There have been scanty results on antimicrobial susceptibility of common causative microorganisms of bacterial pericarditis; most studies had small sample sizes and were performed decades ago. Methodology: This prospective study surveyed the causative bacteria in infectious pericardial effusions and their antimicrobial susceptibility among 320 consecutive cardiac patients who underwent pericardiocentesis at Tehran Heart Center between 2007 and 2012, using the European Society of Cardiology (ESC)'s criteria. Results: Staphylococcus spp. (S. epidermidis, S. aureus, S. haemolyticus) were the main causative organisms isolated from cultures of pericardial effusion samples. Other causative organisms were Streptococcus spp., Enterococcus faecium, Pseudomonas aeruginosa, and Acinetobacter baumannii. In the cultures studied, 35% methicillin-resistant Staphylococcus epidermidis (MRSE) and 42.9% methicillinresistant Staphylococcus aureus (MRSA) were detected. The most effective antimicrobial agents in S. epidermidis were gentamicin, ciprofloxacin, and cefoxitin. Clindamycin was relatively effective. S. aureus was highly susceptible to clindamycin and erythromycin. In cases of S. haemolyticus infection, clindamycin, erythromycin, cefoxitin, and ciprofloxacin were effective antibiotics. Conclusions: In order to diminish the nascence and extension of antimicrobial-resistant pathogens, logical and optimized antimicrobial usage and monitoring in hospitals are highly recommended. It is incumbent on healthcare systems to determine current local resistance patterns by which to guide empiric antimicrobial therapy for specific infections and microorganism types.

show abstract

Patterns of antimicrobial resistance in a surgical intensive care unit of a university hospital in Turkey

Cited by 39 publications

References 24 publications

Patterns of Antimicrobial Resistance Among Intensive Care Unit Patients of A Private Medical College Hospital in Dhaka

Patterns of Antimicrobial Resistance Among Intensive Care Unit Patients of A Private Medical College Hospital in Dhaka

Antimicrobial susceptibility patterns among bacteria isolated from intensive care units of the largest teaching hospital at the northwest of Iran

Bacterial pericarditis and antimicrobial resistance at the Tehran Heart Center, Iran

Contact Info

Product

Resources

About