Patterns of Childhood Body Mass Index Percentile Gains as Predictors of Adolescent Body Mass Index, Waist Circumference, and Blood Pressure

Bichteler, Anne; Barton, Jennifer M.; Lumeng, Julie C.; Gershoff, Elizabeth T.

doi:10.1016/j.acap.2021.11.015

Cited by 2 publications

(1 citation statement)

References 25 publications

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“…Some anthropometric measures were usually used to evaluate the risk of cardiovascular diseases and metabolic syndrome [ 10 – 14 ]. By combining these anthropometric measures with biochemical measures, some novel lipid indicators can be established.…”

Section: Introductionmentioning

confidence: 99%

Novel lipid indicators and the risk of type 2 diabetes mellitus among Chinese hypertensive patients: findings from the Guangzhou Heart Study

Deng

et al. 2022

Cardiovasc Diabetol

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Background Data are limited on whether several easily measured indices are independent predictors of type 2 diabetes mellitus (T2DM) in hypertensive patients. This study aimed to assess the association of hypertriglyceridemic-waist phenotype, triglyceride glucose (TyG) index, lipid accumulation product (LAP), and visceral adiposity index (VAI) with T2DM risk in hypertensive patients. Methods This cross-sectional study included 5321 hypertensive patients from the baseline survey of the Guangzhou Heart Study. Face-to-face questionnaire survey, physical examination, and fasting blood sample collection were completed for all subjects. Odds ratio (OR) with 95% confidence interval (95% CI) were calculated by using the logistic regression model. The potential nonlinear relationship was examined using restricted cubic spline regression. Results The prevalence of T2DM was 19.98% among hypertensive patients. After adjusting for confounders, participants with elevated triglyceride levels and enlarged waist circumference (HTGW) were associated with a 2.57-fold risk of T2DM (OR 2.57, 95% CI 2.05, 3.23). When comparing with subjects within the lowest quartile of the indices, those in the highest quartile of TyG, LAP, and VAI were associated with 5.35-fold (95% CI 4.33, 6.64), 2.65-fold (95% CI 2.11, 3.34), and 2.17-fold (95% CI 1.77, 2.67) risk of T2DM after adjusting for confounders. Every 1-unit increment of TyG, LAP, and VAI was associated with 81%, 38%, and 31% increased risk of T2DM, respectively. The nonlinear association was observed for TyG, LAP, and VAI (all PNon-linear < 0.001). Conclusions The results found that among hypertensive patients, HTGW and a higher level of TyG, LAP, and VAI were associated with an elevated risk of T2DM. The findings suggested that HTGW, TyG, LAP, and VAI may serve as simple and effective tools for T2DM risk assessment in the prevention and management of main chronic diseases.

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Section: Introductionmentioning

confidence: 99%

Novel lipid indicators and the risk of type 2 diabetes mellitus among Chinese hypertensive patients: findings from the Guangzhou Heart Study

Deng

et al. 2022

Cardiovasc Diabetol

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Influence of puberty on relationships between body composition and blood pressure: a cross-sectional study

et al. 2023

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Background: Fat mass (FM) and fat-free mass (FFM) are positively associated with blood pressure (BP) in youth. Yet, how puberty, independent of age, affects these relationships remains unclear. Given puberty may be a crucial period for cardiometabolic health, we examined how pubertal development moderates the associations of FM/FFM with BP. Methods: Pubertal development, resting BP, and body composition were assessed in a convenience sample of youth (5.5-17y). General linear models were conducted to assess if pubertal development moderated the relationships between FM/FFM and systolic/diastolic BP standardized for age, sex, and height (SBP z /DBP z ). Results: Among participants ( N =1,405; age: M =13.3±2.9y; 65.4% female; 53.2% racial/ethnic minority), FM/FFM were positively associated with SBPz and DBPz ( ps ≤.02). Pubertal development moderated the associations between FFM and BPz ( ps ≤.01), but not FM ( ps >.43). For early/mid and late pubertal participants, there were positive associations between FFM and BP (DBP z : βs=.10-.18, ps ≤.01; SBP z : βs=.33-.43, ps <.001); however, these relationships were attenuated, especially for prepubertal DBP z (DBP z : β=.01, p =.91; SBP z : β=.24, p =.001). Conclusions: Puberty moderated the relationships between FFM and SBP z /DBP z in analyses that separately modeled the contributions of age and sex. These data suggest that the FFM-DBP z association may potentially be impacted by increasing sex hormone concentrations during puberty.

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Patterns of Childhood Body Mass Index Percentile Gains as Predictors of Adolescent Body Mass Index, Waist Circumference, and Blood Pressure

Cited by 2 publications

References 25 publications

Novel lipid indicators and the risk of type 2 diabetes mellitus among Chinese hypertensive patients: findings from the Guangzhou Heart Study

Novel lipid indicators and the risk of type 2 diabetes mellitus among Chinese hypertensive patients: findings from the Guangzhou Heart Study

Influence of puberty on relationships between body composition and blood pressure: a cross-sectional study

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