“…123 Ovulation frequency and pregnancy rates are reduced undeniably as the human female ages, but an individual 45 years old still may be regularly ovulatory. 124 Ovulation may have occurred as late as the final menses in three of eight women, but no evidence of ovulation after menopause existed. 79 In the immediate postmenopausal period, 20% to 40% of women studied had estrogen levels consistent with follicular development, 125,126 although by 2 to 3 years after menopause, estrogen levels generally fall into the castrate range.…”