Patterns of Genetic Architecture for Life-History Traits and Molecular Markers in a Subdivided Species

Morgan, Kendall; Hicks, Justin; Spitze, Ken; Latta, Leigh C.; Pfrender, Michael E.; Weaver, Casse S.; Ottone, Marco; Lynch, Michael

doi:10.1554/0014-3820(2001)055[1753:pogafl]2.0.co;2

Cited by 8 publications

References 33 publications

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Genetic control of male production in Daphnia pulex

Molinier

Zhao

et al. 2019

Proc. Natl. Acad. Sci. U.S.A.

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Daphnia normally reproduce by cyclical parthenogenesis, with offspring sex being determined by environmental cues. However, some females have lost the ability to produce males. Our results demonstrate that this loss of male-producing ability is controlled by a dominant allele at a single locus. We identified the locus by comparing whole-genome sequences of 67 nonmale-producing (NMP) and 100 male-producing (MP) clones from 5 Daphnia pulex populations, revealing 132 NMP-linked SNPs and 59 NMP-linked indels within a single 1.1-Mb nonrecombining region on chromosome I. These markers include 7 nonsynonymous mutations, all of which are located within one unannotated protein-coding gene (gene 8960). Within this single gene, all of the marker-linked NMP haplotypes from different populations form a monophyletic clade, suggesting a single origin of the NMP phenotype, with the NMP haplotype originating by introgression from a sister species, Daphnia pulicaria. Methyl farnesoate (MF) is the innate juvenile hormone in daphnids, which induces the production of males and whose inhibition results in female-only production. Gene 8960 is sensitive to treatment by MF in MP clones, but such responsiveness is greatly reduced in NMP clones. Thus, we hypothesize that gene 8960 is located downstream of the MF-signaling pathway in D. pulex, with the NMP phenotype being caused by expression change of gene 8960.

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Genetic control of male production in Daphnia pulex

Molinier

Zhao

et al. 2019

Proc. Natl. Acad. Sci. U.S.A.

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Evolutionary Genomics of Sister Species Differing in Effective Population Sizes and Recombination Rates

Pfrender

Lynch

2023

Preprint

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Studies of closely related species with known ecological differences provide exceptional opportunities for understanding the genetic mechanisms of evolution. Here, we compared population-genomics data between D. pulex and D. pulicaria, two reproductively compatible sister species experiencing ecological speciation, the first largely confined to intermittent ponds and the second to permanent lakes in the same geographic region. D. pulicaria has lower genome-wide nucleotide diversity, a smaller effective population size, higher incidence of private alleles, and substantially more linkage-disequilibrium than D. pulex. Functional enrichment analysis revealed that positively selected genes in D. pulicaria are enriched in potentially aging-related categories such as cellular homeostasis, which may explain the extended lifespan in D. pulicaria. We also found that opsin-related genes, which may mediate photoperiodic responses, are under different selection pressures in these two species. Additionally, genes involved in mitochondrial functions, ribosomes, and responses to environmental stimuli are found to be under positive selection in both species. Our results provide insights into the physiological traits that differ within this regionally sympatric sister-species pair that occupies unique microhabitats.

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Comparison between Q_STand Φ_STindices in an endangeredBoswellia serrataRoxb: Implications for conservation

Mahesh

Kumar

Vaishnav

et al. 2018

Preprint

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9Boswellia serrata, an economically important indigenous tree of dry deciduous forests, provides 10 oleoresin gum of pharmaceutical significance and excellent pulp for paper industries, but faces 11 threat to extinction due to poor natural regeneration and commercial exploitation. 240 12 individuals of the species representing 12 locations of its natural distribution in central India 13 were investigated to compare the genetic differentiation indices, Q ST for GBH and wood fiber 14 length and ϕ ST for neutral (RAPD+ISSR) markers. The comparison for paired locations was more 15 informative than for metapopulation. The most paired locations were either under the stabilizing 16 selection (Q ST (L) < ɸ ST (L)) or in the genetic drift (Q ST (L) = ɸ ST (L)) whereas a relatively small 17 number of paired locations was under the divergent selection (Q S T (L) > ɸ ST (L)). The 18 comparison for the metapopulation generating only a single trend of Q ST (P) > ɸ ST (P) is, 19 therefore, misleading. For conservation, the genetically deficit locations (Q ST (L) < ɸ ST (L) and 20 Q ST (L) = ɸ ST (L)) of B. serrata warrant for reinforcement of their genetic diversity by 21 introduction of genotypes from other genetically divergent locations (Q ST (L) > ɸ ST (L)), which 22 would check the fragmentation and genetic drift, resulting in reproductive vigour, natural 23 regeneration and reverse the endangered status of the species.24

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Patterns of Genetic Architecture for Life-History Traits and Molecular Markers in a Subdivided Species

Cited by 8 publications

References 33 publications

Genetic control of male production in Daphnia pulex

Genetic control of male production in Daphnia pulex

Evolutionary Genomics of Sister Species Differing in Effective Population Sizes and Recombination Rates

Comparison between Q_STand Φ_STindices in an endangeredBoswellia serrataRoxb: Implications for conservation

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Patterns of Genetic Architecture for Life-History Traits and Molecular Markers in a Subdivided Species

Cited by 8 publications

References 33 publications

Genetic control of male production in Daphnia pulex

Genetic control of male production in Daphnia pulex

Evolutionary Genomics of Sister Species Differing in Effective Population Sizes and Recombination Rates

Comparison between QSTand ΦSTindices in an endangeredBoswellia serrataRoxb: Implications for conservation

Contact Info

Product

Resources

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Comparison between Q_STand Φ_STindices in an endangeredBoswellia serrataRoxb: Implications for conservation