Patterns of Obesity during Anti-cancer Chemotherapy in Children with Acute Lymphoblastic Leukemia

Ko, Mi Seon; Kim, Jung Yun; Lim, Yeon Jung; Lee, Young Ho; An, Hye Sung; Yoo, Jae Ho; Shin, Jeh Hoon

doi:10.5045/kjh.2008.43.2.77

Cited by 3 publications

(3 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One previous study also based on Korean children with ALL found a trend towards continued increase in BMI even after treatment completion19).…”

Section: Discussionmentioning

confidence: 89%

“…These results are in contrast to those of similar studies of obesity in childhood ALL patients who completed treatment with chemotherapy only, in which a significant portion of patients studied were found to be either overweight or obese at treatment completion 17 , 18) . One previous study also based on Korean children with ALL found a trend towards continued increase in BMI even after treatment completion 19) .…”

Section: Discussionmentioning

confidence: 89%

See 1 more Smart Citation

Evaluation of changes in random blood glucose and body mass index during and after completion of chemotherapy in children with acute lymphoblastic leukemia

et al. 2012

View full text Add to dashboard Cite

PurposeImproved survival of patients with childhood acute lymphoblastic leukemia (ALL) has drawn attention to the potential for late consequences of previous treatments among survivors, including metabolic syndrome. In this study, we evaluated changes in 3 parameters, namely, random blood glucose, body mass index (BMI), and Z score for BMI (Z-BMI), in children with ALL during chemotherapy and after completion of treatment.MethodsPatients newly diagnosed with ALL from January, 2005 to December, 2008 at Saint Mary's Hospital, The Catholic University of Korea, who completed treatment with chemotherapy only were included (n=107). Random glucose, BMI, and Z-BMI were recorded at 5 intervals: at diagnosis, before maintenance treatment, at completion of maintenance treatment, and 6 and 12 months after completion of maintenance treatment. Similar analyses were conducted on 2 subcohorts based on ALL risk groups.ResultsFor random glucose, a paired comparison showed significantly lower levels at 12 months post-treatment compared to those at initial diagnosis (P<0.001) and before maintenance (P<0.001). The Z-BMI score was significantly higher before maintenance than at diagnosis (P<0.001), but decreased significantly at the end of treatment (P<0.001) and remained low at 6 months (P<0.001) and 12 months (P<0.001) post-treatment. Similar results were obtained upon analysis of risk group-based subcohorts.ConclusionFor a cohort of ALL patients treated without allogeneic transplantation or cranial irradiation, decrease in random glucose and Z-BMI after completion of chemotherapy does not indicate future glucose intolerance or obesity.

show abstract

“…One previous study also based on Korean children with ALL found a trend towards continued increase in BMI even after treatment completion19).…”

Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 89%

Evaluation of changes in random blood glucose and body mass index during and after completion of chemotherapy in children with acute lymphoblastic leukemia

et al. 2012

View full text Add to dashboard Cite

show abstract

“…Otherinvestigators found metabolic syndrome is prevalent in 12.6-39% of childhood cancer survivors 10) . To date, very limited studiesin Korea have focused on the possible relationship between the treatment of childhood cancer and an increased risk of developing metabolic syndrome [11][12][13] . Moreover, most of these studies only include components of metabolic syndrome, such as obesity, or endocrine abnormalities.…”

Section: Metabolic Syndromementioning

confidence: 99%

Late physical effects of childhood cancer survivors

Lee

2010

Korean J Pediatr

Self Cite

View full text Add to dashboard Cite

= Abstract = Advances in research and medical and supportive care have contributed to a growing population of adults formerly treated for childhood cancer. History of cancer and its therapy can have significant life-long health implications. Late effects of cancer therapy can be insidious on onset, occur outside the pediatric age, and contribute to premature morbidity and mortality. In this review, I have focused on the key long-term effects of pediatric cancer therapy, particularly on the metabolic syndrome, including cardiopulmonary complications, infertility, and secondary neoplasm. (Korean J Pediatr 2010;53:477-480)

show abstract

Glucose metabolism abnormalities among pediatric acute lymphoblastic leukemia survivors: Assessment and relation to body mass index and waist to hip ratio

El-Rashedy¹,

Ragab²,

Badr³

et al. 2013

Egyptian Pediatric Association Gazette

View full text Add to dashboard Cite

Patterns of Obesity during Anti-cancer Chemotherapy in Children with Acute Lymphoblastic Leukemia

Cited by 3 publications

References 18 publications

Evaluation of changes in random blood glucose and body mass index during and after completion of chemotherapy in children with acute lymphoblastic leukemia

Evaluation of changes in random blood glucose and body mass index during and after completion of chemotherapy in children with acute lymphoblastic leukemia

Late physical effects of childhood cancer survivors

Glucose metabolism abnormalities among pediatric acute lymphoblastic leukemia survivors: Assessment and relation to body mass index and waist to hip ratio

Contact Info

Product

Resources

About