Patterns of oral anticoagulant use and outcomes in Asian patients with atrial fibrillation: a post-hoc analysis from the GLORIA-AF Registry

Country and health expenditure are major predictors of withholding anticoagulation in atrial fibrillation patients at high risk of stroke

“…However, recent studies have shown that OACs continue to be underused particularly in Asian countries. 12 Our analysis was limited to the examination of antithrombotic agents chosen by treating physicians for the initial treatment of newly diagnosed AF, and did not consider dosing, time on treatment, or possible changes in treatments over time. Moreover, because treatment was not randomly assigned, unobserved baseline confounding cannot be excluded and our inferences should not be interpreted as causal.…”

“…[7][8][9][10][11] Importantly, OACs continue to be underused in many countries. 12 Oral anticoagulants (OACs) should be used judiciously because they increase the risk of bleeding. Clinical guidelines therefore recommend the use of stroke risk prediction scores (eg, CHA 2 DS 2 -VASc Score) to provide individualised treatment.…”