Patterns of skin metastases: a review of 25 years' experience at a single cancer center

Abstract

This is the largest review of skin metastases in the United States in the past 25 years. We found the primary cancers that metastasize to the skin have changed in frequency from previous studies. Our data are helpful in indicating which cancers have the strongest predilection for skin metastasis. Identification of these cancers can help both the clinician and patient detect early signs of metastases, which may allow for earlier diagnosis, implementation of therapy, and possible prolonged survival.

Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report

“…Gastric cancer constitutes about %2.2 of all skin metastasis cases [13]. Incidence of skin metastasis in all gastric cancers is 0.8% and is considered very rare.…”

Cutaneous Metastases of Internal Malignancies: A Retrospective Study from a Tertiary Care Centre in Sub-Himalayan Region

“…As seen in a study by Wong adenocarcinomas (22.7%) were the commonest tumour showing CM followed by lobular carcinoma (4.7%), and non-adenocarcinoma (squamous cell carcinoma [12.2%] and malignant melanoma [5.2%]). [17] In our study adenocarcinoma was primary tumour histopathologic variant in 57.1 % cases. Cutaneous metastases are known to frequently occur in anatomical areas close to the primary tumour.…”

Isolated Nail Dystrophy: An Unlikely Presentation of Metastatic Renal Cell Carcinoma

“…Primary malignancies that most frequently metastasize to the skin are breast (32.7% of all skin metastases seen), followed by bronchus and lung (13.2%), skin (most commonly melanoma; 9.5%), lymph nodes (7.5%), oral cavity/pharynx/larynx (6.2%), blood and bone marrow (5.5%), and colorectal (4.2%) [8]. Urologic cancers are less likely to metastasize to the skin compared to other primary malignancies, with a reported 1.1% of urologic malignancies metastasizing to skin [3].…”