“…We prefer to use central venous access, trying to maintain a continuous blood flow in order to prevent prolonging the apheresis procedure, and thus limiting the time to avoid potential complications that may occur, in addition to providing comfort for the donor. Central venous catheter placement has been associated with adverse events such as bleeding, infections, thrombotic events, and pneumothorax , however, in our cases, no serious adverse events related to the placement and use of a central venous catheter were observed. In each case, the catheter was placed by a group of expert physicians dedicated to providing central venous access with extensive experience in the procedure.…”