Patterns of Valvular Involvement in Rheumatic Heart Disease patients taking Benzathine Penicillin at Shahid Gangalal National Heart Centre, Kathmandu, Nepal

Malla, Rabi; Thapaliya, Suman; Gurung, Prakash; Bogati, Amit; Khadka, Sunita; Shrestha, Sajana; Rajbhandari, Sujeeb; Adhikari, Chandra Mani

doi:10.3126/njh.v13i2.15560

Cited by 7 publications

(6 citation statements)

References 5 publications

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“…2 In the present study Pure Mitral Stenosis (64.57%) was the most common lesion followed by pure Aortic Stenosis (8.86%), pure Mitral regurgitation (7.14%), pure Aortic Regurgitation (1.43%). These results were in accordance with the study done by Rabi Malla et al which showed MS as the most common valvular lesion, 13 However CN Manjunath 14 stated that MR was much more common than MS in the paediatric age group (<19 years) whereas in adults >20 years, MS was twice as common as MR. CN Manjunath also reported Rheumatic connection created the leading cause of valvular damage followed narrowly by myxomatous or mitral valve prolapse, comparable to the surgical series of Olson 15 (31% and 38% respectively) and Duren 16 (40% and 33% respectively).…”

Section: Discussionsupporting

confidence: 91%

A Study of Pattern of Cardiac Valvular Involvement in Patients With Rheumatic Heart Disease by Using 2-D Echocardiography

Kumar¹,

Kalra²,

Gupta³

2019

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BACKGROUND Rheumatic Heart Disease is estimated to affect more than 15 million people worldwide and leads to 2,30,000 deaths every year. 1 More than 80% of children younger than 15 years of age grow up in the regions of the world where RHD is endemic. 2 In developing countries the course is more violent with severe valvular pathological lesions necessitating surgery in young children. 3 METHODS A total of 550 patients attending Subharti Medical College with confirmed valvular heart disease were studied for a period of 1 year using clinical and echocardiographic examination. 350 of these patients had rheumatic heart disease as the aetiology of valvular disease. RESULTS In this study, we used clinical and echocardiographic examination over a period of 1 year and evaluated 550 patients with confirmed valvular heart disease 350 of whom were diagnosed to have rheumatic heart diseases (RHD). 57.14% of these were females and the majority (26.28%) were in the age group of 16-20 years at the time of diagnosis. Our study also revealed that a vast majority of these patients (291) had mitral valve involvement (83.14%) of which 226 patients had isolated mitral stenosis (64.57%). The pulmonary valve was the least affected of all (1.71%). There were no patients with pure tricuspid stenosis. Tricuspid regurgitation (2.28%), pulmonary regurgitation (1.71%). Left sided lesions were far more common with pure MS (64.57%), pure MR (7.14%) and isolated AR and AS at 1.43% and 8.86%, respectively. The mixed valvular lesions were 14%. CONCLUSIONS Rheumatic heart disease was found to be more prevalent in females in the age group 16-20 years and involving the left side of heart more commonly. Involvement of the mitral valve was found in the majority of these patients.

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Section: Discussionsupporting

confidence: 91%

A Study of Pattern of Cardiac Valvular Involvement in Patients With Rheumatic Heart Disease by Using 2-D Echocardiography

Kumar¹,

Kalra²,

Gupta³

2019

jebmh

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“…Mitral valve disease was more common in female whereas aortic valve disease was more common in male. 13 In another study done by Rayamajhi A et al, mitral valve was the most commonly affected valve (82%). 14 In our study, isolated mitral valve was affected more (46.05%) than isolated aortic valve (1.9%) which was statistically significant in female patients with p value 0.013.…”

Section: Affected Valve and Valvular Lesionmentioning

confidence: 99%

Pattern of rheumatic heart disease in patients admitted at tertiary care centre of Nepal

2018

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“…The course of RHD is more rapid than in degenerative disease and predisposes to cardiac failure, secondary endocarditis, atrial fibrillation and stroke [46]. Most patients with RHD have mixed mitral valve stenosis and regurgitation [47]. Aortic regurgitation is seen in less than 50% of the patients and it is found almost always in combination with mitral valve disease; aortic stenosis is rare [48].…”

Section: Discussionmentioning

confidence: 99%

Cardiac ultrasound in resource-limited settings (CURLS): towards a wider use of basic echo applications in Africa

et al. 2019

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Background: Point-of-care ultrasound is increasingly being used as a diagnostic tool in resource-limited settings. The majority of existing ultrasound protocols have been developed and implemented in high-resource settings. In sub-Saharan Africa (SSA), patients with heart failure of various etiologies commonly present late in the disease process, with a similar syndrome of dyspnea, edema and cardiomegaly on chest X-ray. The causes of heart failure in SSA differ from those in high-resource settings. Point-of-care ultrasound has the potential to identify the underlying etiology of heart failure, and lead to targeted therapy. Based on a literature review and weighted score of disease prevalence, diagnostic impact and difficulty in performing the ultrasound, we propose a context-specific cardiac ultrasound protocol to help differentiate patients presenting with heart failure in SSA. Results: Pericardial effusion, dilated cardiomyopathy, cor pulmonale, mitral valve disease, and left ventricular hypertrophy were identified as target conditions for a focused ultrasound protocol in patients with cardiac failure and cardiomegaly in SSA. By utilizing a simplified 5-question approach with all images obtained from the subxiphoid view, the protocol is suitable for use by health care professionals with limited ultrasound experience. Conclusions: The "Cardiac ultrasound for resource-limited settings (CURLS)" protocol is a context-specific algorithm designed to aid the clinician in diagnosing the five most clinically relevant etiologies of heart failure and cardiomegaly in SSA. The protocol has the potential to influence treatment decisions in patients who present with clinical signs of heart failure in resource-limited settings outside of the traditional referral institutions.

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Patterns of Valvular Involvement in Rheumatic Heart Disease patients taking Benzathine Penicillin at Shahid Gangalal National Heart Centre, Kathmandu, Nepal

Cited by 7 publications

References 5 publications

A Study of Pattern of Cardiac Valvular Involvement in Patients With Rheumatic Heart Disease by Using 2-D Echocardiography

A Study of Pattern of Cardiac Valvular Involvement in Patients With Rheumatic Heart Disease by Using 2-D Echocardiography

Pattern of rheumatic heart disease in patients admitted at tertiary care centre of Nepal

Cardiac ultrasound in resource-limited settings (CURLS): towards a wider use of basic echo applications in Africa

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