PC-PE Hollow-Fiber Membrane

Abstract

Polyether-polycarbonate hollow fibers, spun by the phase inversion method, yield a dialysis membrane with a limited ultrafiltration coefficient but high diffusive permeability. Dialysers are made out of this membrane and are sterilized by gamma radiation. The dialysers show controlled ultrafiltration and clearance values for smaller molecular weight substances in the range of cellulosic membranes, but for larger molecular weight substances the clearances are higher. Correlation for ultrafiltration and clearance values, measured in saline and whole blood, indicate low interactions between blood and membrane.

Polymeric Membranes for Medical Applications

“…The first one consists in the placement of spacer yarns between the fibers in order to create a better distribution path of the dialysate solution [18]. In the second technique [19] a special fiber crossing with a certain angle is applied during bundle formation to get even dialysate distribution. The third is fiber undulation to form a waved shape of the hollow fibers that prevents dense packing of the fibers and maintains the dialysate path open in the entire cross sectional area of the bundle (see Fig.…”