PCL-based hydrophobic chains grafted with two PEG-based hydrophilic branches: fluorescence and dynamic light scattering studies

Novel amphiphilic (AB)3‐type star block polymer: Synthesis and micellization study

“…Thus, 1,2,3-triazole derivatives play an intriguing role in the development of new drugs. 27 According to our previous works, 29,30 to prepare an amphiphilic copolymer, the CuAAC reaction provides a route to connect the hydrophilic segments of PEG and the hydrophobic segments of PCL. In the present work, an amphiphilic (AB) 3 -type star block polymer containing hydrophilic PEG and hydrophobic PCL segments is synthesized.…”

Synthesis of PEGylated amphiphilic block copolymers with pendant linoleic moieties by combining ring‐opening polymerization and click chemistry

“…[ 21–25 ] Notably, CuAAC has demonstrated utility in the synthesis of intricate structures, including dendrimers, [ 26,27 ] cyclic macromolecules, [ 28,29 ] and unconventional architectures such as H‐shaped copolymers. [ 30 ] Şanal et al demonstrated that PCL‐containing azide groups can be modified through grafting PEG chains via click chemistry, obtaining a material with improved hydrophilicity. [ 31 ]…”

“…[21][22][23][24][25] Notably, CuAAC has demonstrated utility in the synthesis of intricate structures, including dendrimers, [26,27] cyclic macromolecules, [28,29] and unconventional architectures such as H-shaped copolymers. [30] Şanal et al demonstrated that PCL-containing azide groups can be modified through grafting PEG chains via click chemistry, obtaining a material with improved hydrophilicity. [31] The implementation of CuAAC "click" reactions to produce polymeric materials is hindered by challenges, such as large catalyst requirements, complicated purification processes, prolonged reaction times, and elevated energy demands.…”