Pcn190 Global Distribution of Clinical Trials for Targeted Cancer Therapies

Abstract

Objectives: Cervical cancer-related morbimortality and survival is marked by inequalities across different geographical areas. We investigated the association between macroregion of residence and survival in women diagnosed with cervical cancer who underwent cancer treatment in the public health system (SUS) between 2002 and 2015 in Minas Gerais, Brazil. Methods: Non-concurrent prospective study with data from the National Database in Oncology (Base Onco), developed through deterministic-probabilistic pairing of SUS information systems. We identified women aged over 18 years, diagnosed with cervical cancer between 2002 and 2010, who underwent radiotherapy and/or chemotherapy and who were living in Minas Gerais. We estimated five-year overall and cancer-specific survival probabilities by the Kaplan-Meier method. Extended Cox models were employed to assess the association between macroregion of residence and overall and cancer-specific death risk. Results: A total of 5,613 patients were included. Five-year overall and cancer-