PCR coupled with mass-spectrometry for detection of Clostridium difficile virulence markers during the emergence of ribotype 027 in Bucharest area

Abstract

In recent years Clostridium difficile infection (CDI) has represented a serious public health issue

Antibiotic susceptibility and resistance profiles of Romanian Clostridioides difficile isolates

“…In Romania, high rates persisted since first outbreaks occurred in 2011, with PR 027 as prevalent among the strain types causing outbreaks [25][26][27]. One of the main causes for the persistence of high CDI rates may be the over prescription of wide spectrum antibiotics, still an issue in our country.…”