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Abstract. Superficial mycoses are one of the main reasons for consulta-tion in the dermatological area. In recent years, the therapeutic effectiveness of ozonated oils in fungal infections has been verified in different countries due to its broad germicidal and antifungal spectrum. The objective is to evaluate the efficacy of the use of ozonated sunflower oil in the treatment of superficial mycoses in patients of the Mycology consultation at the Dermatology Service of the Hospital Vargas de Caracas, Instituto Autonómo de Biomedicina “Dr. Ja-cinto Convit”. A cross-sectional descriptive, experimental study was conducted, where 36 patients diagnosed with superficial mycosis and ten healthy subjects were evaluated. Of the group of 36 patients, 26 were treated with ozonated sun-flower oil (AGO) and ten patients with non-ozonized sunflower oil (AGNO). Ten healthy individuals represented the AGO sensitivity control. The most frequent superficial mycosis evaluated in the AGO group was tinea corporis (31%), fol-lowed by denture stomatitis (23%) and for the AGNO group, tinea pedis (50%). Regarding the etiological agent, an improvement with the AGO treatment of 86% for Candida albicans and 60% for the Trichophyton rubrum complex was evidenced at week eight of treatment. It is concluded that the antifungal effect of AGO is more significant for the genus Candida spp than for dermatophytes, evidencing a total improvement of the lesions with six weeks of treatment.
Abstract. Superficial mycoses are one of the main reasons for consulta-tion in the dermatological area. In recent years, the therapeutic effectiveness of ozonated oils in fungal infections has been verified in different countries due to its broad germicidal and antifungal spectrum. The objective is to evaluate the efficacy of the use of ozonated sunflower oil in the treatment of superficial mycoses in patients of the Mycology consultation at the Dermatology Service of the Hospital Vargas de Caracas, Instituto Autonómo de Biomedicina “Dr. Ja-cinto Convit”. A cross-sectional descriptive, experimental study was conducted, where 36 patients diagnosed with superficial mycosis and ten healthy subjects were evaluated. Of the group of 36 patients, 26 were treated with ozonated sun-flower oil (AGO) and ten patients with non-ozonized sunflower oil (AGNO). Ten healthy individuals represented the AGO sensitivity control. The most frequent superficial mycosis evaluated in the AGO group was tinea corporis (31%), fol-lowed by denture stomatitis (23%) and for the AGNO group, tinea pedis (50%). Regarding the etiological agent, an improvement with the AGO treatment of 86% for Candida albicans and 60% for the Trichophyton rubrum complex was evidenced at week eight of treatment. It is concluded that the antifungal effect of AGO is more significant for the genus Candida spp than for dermatophytes, evidencing a total improvement of the lesions with six weeks of treatment.
Introducción: Las dermatofitosis constituyen del 70 al 80 % de todas las micosis. Cuba presenta un clima favorable para su desarrollo, pero hasta el momento se desconoce su peso como problema de salud en el país. Objetivo: Describir los agentes causales de la dermatofitosis y su posible relación con variables clínico-epidemiológicas en población adulta. Metodología: Estudio descriptivo entre septiembre de 2021 y junio de 2022 en pacientes que asistieron a la consulta de dermatología del Hospital General “Calixto García”. Se colectaron datos clínico-epidemiológicos a través de una encuesta y muestras clínicas para estudio micológico, las que se procesaron mediante métodos convencionales. Los resultados se expresaron a través de frecuencias absolutas y porcentajes. Las diferencias se consideraron significativas cuando p<0,05 para un intervalo de confianza del 95 %. Resultados: De 1 223 pacientes, 112 cumplieron los criterios de inclusión. De ellos, 29 (25,9 %) resultaron positivos al estudio micológico. La forma clínica más frecuente fue la tiña de los pies, seguida por la onicomicosis. Estas predominaron en hombres mestizos entre 19 y 29 años que practicaban algún deporte. La coincidencia de resultados entre el examen directo y el cultivo fue del 62,5 % (Kappa = 0,4). El agente etiológico mayoritario fue Trichophyton rubrum (75,8 %), seguido por Trichophyton interdigitale, Trichophyton tonsurans (10,3 % cada uno) y Microsporum canis (3,4 %). Conclusiones: A pesar de las limitaciones del estudio, los resultados reafirman la necesidad de estimar la magnitud de la dermatofitosis en Cuba, que permitan implementar medidas para su prevención y control.
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