Pcv99 the Role of Illness Burden and Medication Beliefs in Medication Compliance of Elderly With Hypertension

Rajpura, JR; Nayak, R.

doi:10.1016/s1098-3015(10)72818-7

Cited by 1 publication

(1 citation statement)

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“…These were investigated further and authors were contacted where necessary to clarify whether unpublished work had led to publications [39] – [45] . Sixteen studies [44] , [46] – [59] [60] had since been published, fifteen of which already formed part of the included list and one additional eligible study was available online early [61] . Six papers reported data on samples which overlapped with included studies [62] – [67] , and four were protocols for ongoing studies [68] – [71] .…”

Section: Resultsmentioning

confidence: 99%

Understanding Patients’ Adherence-Related Beliefs about Medicines Prescribed for Long-Term Conditions: A Meta-Analytic Review of the Necessity-Concerns Framework

Horne¹,

Chapman²,

Parham³

et al. 2013

PLoS ONE

916

888

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BackgroundPatients’ beliefs about treatment influence treatment engagement and adherence. The Necessity-Concerns Framework postulates that adherence is influenced by implicit judgements of personal need for the treatment (necessity beliefs) and concerns about the potential adverse consequences of taking it.ObjectiveTo assess the utility of the NCF in explaining nonadherence to prescribed medicines.Data sourcesWe searched EMBASE, Medline, PsycInfo, CDSR/DARE/CCT and CINAHL from January 1999 to April 2013 and handsearched reference sections from relevant articles.Study eligibility criteriaStudies using the Beliefs about Medicines Questionnaire (BMQ) to examine perceptions of personal necessity for medication and concerns about potential adverse effects, in relation to a measure of adherence to medication.ParticipantsPatients with long-term conditions.Study appraisal and synthesis methodsSystematic review and meta-analysis of methodological quality was assessed by two independent reviewers. We pooled odds ratios for adherence using random effects models.ResultsWe identified 3777 studies, of which 94 (N = 25,072) fulfilled the inclusion criteria. Across studies, higher adherence was associated with stronger perceptions of necessity of treatment, OR = 1.742, 95% CI [1.569, 1.934], p<0.0001, and fewer Concerns about treatment, OR = 0.504, 95% CI: [0.450, 0.564], p<0.0001. These relationships remained significant when data were stratified by study size, the country in which the research was conducted and the type of adherence measure used.LimitationsFew prospective longitudinal studies using objective adherence measures were identified.ConclusionsThe Necessity-Concerns Framework is a useful conceptual model for understanding patients’ perspectives on prescribed medicines. Taking account of patients’ necessity beliefs and concerns could enhance the quality of prescribing by helping clinicians to engage patients in treatment decisions and support optimal adherence to appropriate prescriptions.

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