Pd-porphyrin complex-catalyzed allylation of indole with allylic alcohols through C3–C2 coupling

The untold story of starch as a catalyst for organic reactions

“…[128][129][130][131] Indole alkaloids are among the important indole derivatives that can be prepared by the alkylation reaction at the indole C 3 position. 132,133 In 2019, the Mallick research group developed a new protocol including using starch-supported cuprous iodide nanoparticles as catalysts for the 3-allylation reaction of N-substituted indoles (Scheme 37). 134 The authors proposed that the reaction proceeds with an electrophilic mechanism assisted by CuI nanoparticles as a catalyst.…”