Background: this paper presents a first experiment with random generator of drug prices and a first simulation on physicians’ treatment choices (case on pharmacotherapies) for diabetes type II care. It also aims to compare the effects of the price variables according to public versus private health plans on physicians’ choices (Medicare versus commercial Health Plans). Methods: the base line model used is a Mixed Logit model with Random Price variables. A series of experiments with random parameters generations is designed with various sequences and number of draws. The model is tested on a real analytical dataset, extracted from the CDC physician survey (National Ambulatory Care Survey, NAMCS), for patients with diabetes type II without complications, for previous predictive econometrics with ENDEPUS research, Inc. The model uses a first drug choice set with three alternatives: oral agents only, combined therapies, no drug. The choice models introduce qualitative dependent variables and complement the series of cumulative logistic models per disease. The matlab code for the new specification test on the Independence of Irrelevant Alternatives at individual level is modified to fit this type of medical applications. Results: a mixed logit model is run on Stata to estimate main coefficients associated with price variables and socio demographics of diabetic patients; these parameters are then imported into a modified matlab code, based on first experiments of random generators for price; runs compare main parameters of a full choice set versus reduced choice sets of alternatives. It is planned to design more experiments for extended choice sets and widespread applications, to lead to user friendly tools for medical systems. Conclusions: the collaboration with Professor Jerry Hausman on the US market will help with use of results and new ways to adjust the reliability of the selection of alternatives; it may provide additional guidance to the algorithms used by professionals and for health policies.