PDMS Based Thermopnuematic Peristaltic Micropump for Microfluidic Systems

Mamanee, W.; Tuantranont, Adisorn; Afzulpurkar, Nitin; Porntheerapat, N; Rahong, Sakon; Wisitsoraat, Anurat

doi:10.1088/1742-6596/34/1/093

Cited by 19 publications

(13 citation statements)

References 2 publications

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“…Maximum flow rate of 319.6μLmin −1 and a maximum hydrostatic backpressure of 950 Pa (9.5 cm H2O) were exerted by the micropump. Further Mamanee et al, studied the thermo-pneumatic peristaltic micropump for controlling micro liters of fluid flow [7]. Pump structure consists an inlet and outlet, micro-channel, three thermo-pneumatic actuation chambers and three heaters.…”

Section: Introductionmentioning

confidence: 99%

Fabrication and development of magnetically actuated PDMS micropump for drug delivery

Gadad

Shivayyanavar

Viannie

et al. 2018

IOP Conf. Ser.: Mater. Sci. Eng.

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Abstract:Micropump is an essential component used in drug delivery systems to dispense small amounts of liquid into human body in a controlled manner over a period of time. Polydimethylsiloxane (PDMS) is an elastomeric polymer with attractive properties such as nontoxicity, biocompatibility and blood compatibility. Further, its bio-inertness inhibits microbial growth, thereby making it more attractive for biomedical applications. This paper presents the fabrication of a simple, dual-chamber, valveless PDMS micropump with an integrated magnetic actuator for drug delivery applications. The micropump developed in the laboratory consisted of two circular reservoirs provided with end nozzle diffusers. The reservoirs were sealed with a thin PDMS layer and a permanent magnet was attached over it to form the actuation membrane. An external magnet fixed to a rotating DC motor shaft is used to excite the actuation membrane. The magnetic force of attraction and repulsion between the rotating magnet and membrane magnet resulted in a vibrating diaphragm and consequently aids in pumping action. The liquid flow rate through the PDMS micropump depends on the rotational speed of the motor, viscosity of the liquid and the geometry of the micropump. Exhaustive experimental results were obtained with different viscous fluids such as water, ethanol and coconut oil. For these fluids, the motor speeds of the developed PDMS micropump worked satisfactorily. The parameter of interest such as flow rate for water was found to be 1.7 mL/min at a motor speed of 3000 rpm. The highest flow rate of the pump corresponded to the resonant frequency of the actuation membrane which is 14.8 Hz.

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Section: Introductionmentioning

confidence: 99%

Fabrication and development of magnetically actuated PDMS micropump for drug delivery

Gadad

Shivayyanavar

Viannie

et al. 2018

IOP Conf. Ser.: Mater. Sci. Eng.

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“…In recent years, many researchers proposed design and fabrication technologies of valveless peristaltic micropumps [1][2][3][4]. However, valves are one of the most important components in fluidic systems.…”

Section: Introductionmentioning

confidence: 99%

A passive biomimic PDMS valve applied in thermopneumatic micropump for biomicrofluidics

Tang

Lin

et al. 2011

2011 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

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A passive biomimic PDMS valve applied in thermopneumatic micropump is firstly designed and realized. Unlike the conventional peristaltic pumping configuration, the micropump consists of two stacking layers of PDMS on a glass slide. This sandwich-type structure builds up two chambers. A thermopneumatic actuation chamber consists of a heater on the glass slide; the other fluid chamber is connected with inlet and outlet microchannel. A diaphragm between chambers isolates chamber mediums and transmits the thermopneumatic actuation. More importantly, the fluid chamber connects to microchannels via two passive biomimic PDMS valves. .Thus, the fluid is driven and constrained in one way flow by the valves. The two passive biomimic PDMS valves produce one-way as the actuation diaphragm squeezing and releasing the pumping chamber. As the result, the flow rate of thermopneumatic micropump is measured as 100 nL/min.

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“…The actuation can be realized without loosing the flexibility of the membrane, which is critical for tight and leak-free valves. This concept has been realized in different setups, where the pneumatic pressure was delivered from an external device (Lee et al, 2006) or via resistive heating of an encapsulated working fluid (Yoo et al, 2007;Mamanee et al, 2006). In the presented setup we realize a thermo-pneumatically actuated valve with an integrated working fluid reservoir, which can be heated and cooled just by reverting the DC current through a micro Peltier-element.…”

Section: Introductionmentioning

confidence: 99%

Fast thermo-pneumatic actuation of a thin PDMS membrane using a micro Peltier-element for microfluidic applications

Lederer

Hilber

Jakoby

2009

Elektrotech. Inftech.

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In this paper we present a concept for fast thermo-pneumatic actuation of a thin flexible PDMS membrane using a micro Peltier-element for controlling the temperature of the working fluid in a piston-like liquid reservoir. By adjusting the temperature of the working fluid, in our case ethanol, the volumetric thermal expansion is controlled, which is in turn directly coupled to membrane deflection. Pinch-off and subsequent release of a microfluidic channel above the membrane is achieved in a few seconds. The proposed setup can be potentially utilized for the realization of fast and robust microfluidic valves and pumps.Schnelle thermopneumatische Aktuation einer dü nnen PDMS-Membran mittels Mikro-Peltier-Elements fü r mikrofluidische Anwendungen.In diesem Beitrag wird ein Konzept fü r eine schnelle thermopneumatische Aktuation einer dü nnen, flexiblen PDMS-Membran vorgestellt. Dabei wird die Temperatur einer Arbeitsflü ssigkeit in einem kolbenä hnlichen Flü ssigkeitsreservoir mittels eines Mikro-Peltier-Elements gesteuert. Durch Variation der Temperatur der Arbeitsflü ssigkeit, in diesem Fall Ethanol, wird ü ber die volumetrische thermische Ausdehnung direkt eine Auslenkung der Membran erzielt. Das Abschnü ren und anschließende Ö ffnen eines mikrofluidischen Kanals oberhalb der Membran benö tigt nur wenige Sekunden. Das vorgestellte Setup kann fü r die Realisierung von schnellen und robusten mikrofluidischen Ventilen und Pumpen benutzt werden.Schlü sselwö rter: PDMS-Membran; Mikro-Peltier-Element; Arbeitsflü ssigkeit; thermische Ausdehnung

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PDMS Based Thermopnuematic Peristaltic Micropump for Microfluidic Systems

Cited by 19 publications

References 2 publications

Fabrication and development of magnetically actuated PDMS micropump for drug delivery

Fabrication and development of magnetically actuated PDMS micropump for drug delivery

A passive biomimic PDMS valve applied in thermopneumatic micropump for biomicrofluidics

Fast thermo-pneumatic actuation of a thin PDMS membrane using a micro Peltier-element for microfluidic applications

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