Since rapid population growth leads to tall-buildings construction, several studies are conducted regarding effective parameters on tall-structures behavior against wind pressure, which indicate wind speed changes, structures’ damping and environmental context density are effective on structure’s aerodynamic and aerostatic behavior. Accordingly, using CFD, CSD and CARRC, we investigated impact of mentioned factors on structure-wind interaction. Here, several 3D standard models were generated using ABAQUS software, next, wind profile was modeled in atmospheric boundary layer, flow turbulence was simulated by LES method and simulation method was used to transfer non-uniform loads from fluid to structural nodes. Structural damping was also determined by Rayleigh-method. Results show that structures without damping have much higher responses to wind. Furthermore, denser contexts around the structure change wind velocity profile at height and increase maximum displacements and stresses in upper and lower parts; average wind pressure distribution in high-rise buildings is influenced by average wind speed.