Pearls before Swine: Plant-Derived Wastes to Produce Low-Cholesterol Meat from Farmed Pigs—A Bibliometric Analysis Combined to Meta-Analytic Studies

Bertocci, Filippo; Mannino, Giuseppe

doi:10.3390/foods12030571

Cited by 3 publications

(3 citation statements)

References 119 publications

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“…In particular, bibliometric analysis allows for summarizing research trends and identifying research interests, also using author affiliations as potential variables. In addition, it can be used to provide a comparative analysis of scientific productivity at the country, institution, or individual level [38].…”

Section: Bibliometric Analysismentioning

confidence: 99%

The Role of Biogenic Amines in Social Insects: With a Special Focus on Ants

Mannino

Casacci

2023

Insects

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Eusociality represents the higher degree of interaction in insects. This complex social structure is maintained through a multimodal communication system that allows colony members to be flexible in their responses, fulfilling the overall society’s needs. The colony plasticity is supposedly achieved by combining multiple biochemical pathways through the neuromodulation of molecules such as biogenic amines, but the mechanisms through which these regulatory compounds act are far from being fully disentangled. Here, we review the potential function of major bioamines (dopamine, tyramine, serotine, and octopamine) on the behavioral modulation of principal groups of eusocial Hymenoptera, with a special focus on ants. Because functional roles are species- and context-dependent, identifying a direct causal relationship between a biogenic amine variation and behavioral changes is extremely challenging. We also used a quantitative and qualitative synthesis approach to summarize research trends and interests in the literature related to biogenic amines of social insects. Shedding light on the aminergic regulation of behavioral responses will pave the way for an entirely new approach to understanding the evolution of sociality in insects.

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Section: Bibliometric Analysismentioning

confidence: 99%

The Role of Biogenic Amines in Social Insects: With a Special Focus on Ants

Mannino

Casacci

2023

Insects

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“…Other evidence suggests that HMGCR activity increases with LDL starvation and is strongly inhibited with LDL hypersaturation. Although HMGCR mainly aggregates in liver cells, it is also widely distributed in the brain [ 31 ]. Brain sterols are also metabolized by the low-density lipoprotein receptor (LDLR) pathway and distributed in the blood by lipoproteins.…”

Section: Hmgcr-induced Cholesterol Synthesis Mechanismmentioning

confidence: 99%

Mechanisms of 3-Hydroxyl 3-Methylglutaryl CoA Reductase in Alzheimer’s Disease

Zhou,

Wu,

Wang

et al. 2023

IJMS

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Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide and has a high incidence in the elderly. Unfortunately, there is no effective therapy for AD owing to its complicated pathogenesis. However, the development of lipid-lowering anti-inflammatory drugs has heralded a new era in the treatment of Alzheimer’s disease. Several studies in recent years have shown that lipid metabolic dysregulation and neuroinflammation are associated with the pathogenesis of AD. 3-Hydroxyl 3-methylglutaryl CoA reductase (HMGCR) is a rate-limiting enzyme in cholesterol synthesis that plays a key role in cholesterol metabolism. HMGCR inhibitors, known as statins, have changed from being solely lipid-lowering agents to neuroprotective compounds because of their effects on lipid levels and inflammation. In this review, we first summarize the main regulatory mechanism of HMGCR affecting cholesterol biosynthesis. We also discuss the pathogenesis of AD induced by HMGCR, including disordered lipid metabolism, oxidative stress, inflammation, microglial proliferation, and amyloid-β (Aβ) deposition. Subsequently, we explain the possibility of HMGCR as a potential target for AD treatment. Statins-based AD treatment is an ascent field and currently quite controversial; therefore, we also elaborate on the current application prospects and limitations of statins in AD treatment.

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“…This is beneficial for identifying research trends, interests, and variables such as author affiliations. Additionally, a comparative analysis of scientific productivity can also be provided by this tool at the national, institutional, or individual level [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Ethylene: A Modulator of the Phytohormone-Mediated Insect Herbivory Network in Plants

Bungala,

Park,

Dique

et al. 2024

Insects

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Plants have evolved to establish insect herbivory defences by modulating their metabolism, growth, and development. Precise networks of phytohormones are essential to induce those herbivory defences. Gaseous phytohormone ET plays an important role in forming herbivory defences. Its role in insect herbivory is not fully understood, but previous studies have shown that it can both positively and negatively regulate herbivory. This review presents recent findings on crosstalk between ET and other phytohormones in herbivory responses. Additionally, the use of exogenous ETH treatment to induce ET in response to herbivory is discussed.

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Pearls before Swine: Plant-Derived Wastes to Produce Low-Cholesterol Meat from Farmed Pigs—A Bibliometric Analysis Combined to Meta-Analytic Studies

Cited by 3 publications

References 119 publications

The Role of Biogenic Amines in Social Insects: With a Special Focus on Ants

The Role of Biogenic Amines in Social Insects: With a Special Focus on Ants

Mechanisms of 3-Hydroxyl 3-Methylglutaryl CoA Reductase in Alzheimer’s Disease

Ethylene: A Modulator of the Phytohormone-Mediated Insect Herbivory Network in Plants

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