Pectin-Gelatin Complex Coacervates I: Determinants of Microglobule Size, Morphology, and Recovery as Water-Dispersible Powders

McMullen, J.N.; Newton, David W.; Becker, Charles H.

doi:10.1002/jps.2600710608

Cited by 42 publications

(15 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This system has been characterized by Bungenberg de Jong (1949) through measurements of viscosity, turbidity, coacervate volume and electrophoresis. Other combinations which have been investigated are the carbopol-gelatin system (Elgindy & Elegakey I98 l), the pectin-gelatin system (McMullen et al 1982) and the gelatingelatin system (Burgess & Carless 1985). However, to date the sodium carboxymethylcellulose (SCMC)-gelatin system has not been studied.…”

mentioning

confidence: 99%

Characterization of Sodium Carboxymethylcellulose-Gelatin Complex Coacervation by Viscosity, Turbidity and Coacervate Wet Weight and Volume Measurements

Koh

Tucker

1988

Journal of Pharmacy and Pharmacology

View full text Add to dashboard Cite

A sodium carboxymethylcellulose (SCMC) and gelatin coacervation system has been evaluated and characterized and the effects of pH and colloid mixing ratio on the coacervation process investigated. The colloid mixing ratio at which optimum coacervation occurred varied with the coacervation pH. A viscometric investigation of various isohydric SCMC-gelatin mixtures was used to predict optimum conditions for complex coacervation. Optimum coacervation occurred at pH 3.5 at a SCMC-gelatin weight ratio of 3:7 for the SCMC complex coacervation system. Turbidity data confirmed these viscometric results. Coacervate wet weight and volume measurements could not be used to predict optimal coacervation conditions due to changes in the coacervate morphology with mixing ratio. At pH values where coacervation did not occur, the viscosity showed unexpected positive deviations from additive behaviour.

show abstract

mentioning

confidence: 99%

Characterization of Sodium Carboxymethylcellulose-Gelatin Complex Coacervation by Viscosity, Turbidity and Coacervate Wet Weight and Volume Measurements

Koh

Tucker

1988

Journal of Pharmacy and Pharmacology

View full text Add to dashboard Cite

show abstract

“…Microcapsules were prepared by complex coacervation technique according to methods previously described by (Mcmullen, Newton, & Becker, 1982;Mcmullen, Newton, & Becker, 1984) with several modifications. Briefly, 0.5 g of the extract was mixed with 28.5 ml of gelatin solution (5% w/v) at 40 8C (the protein denaturation temperature).…”

Section: Preparation and Characterization Of Microcapsules 231 | mentioning

confidence: 99%

Formulation of stable microcapsules suspensions contentSalvia officinalisextract for its antioxidant activity preservation

Bachir

Zafour

Medjkane

2017

J Food Process Preserv

View full text Add to dashboard Cite

The stabilization of microparticles suspensions is always assured by macromolecules that allow the increasing of dispersing phase viscosity and maintaining the microparticles dispersibility. In this work, the effect of xanthan gum, tragacanth, and sodium alginate on the stability of gelatin–pectin microcapsules suspensions containing sage polyphenols as an active substance was investigated. After polyphenols extraction from Salvia officinalis, their characterization by HPLC‐UV/DAD and their microencapsulation by complex coacervation technique using gelatin and pectin. Three different suspensions of microcapsules were prepared using different polymeric dispersant agents. The suspensions were characterized by laser for particle size, zetametry, viscosimetry, and evaluation of their antioxidant activities was carried out by the DPPH scavenging radical method. Stability study of prepared suspensions was undertaken during 90 days, the results obtained showed that sodium alginate and tragacanth had a better stabilizing effect compared with xanthan gum. After formulation of sage extract, its antioxidant activity increases and its half‐life time increases from 12.75 ± 1.95 days (R2 = .93) to 258.64 ± 21.99 days (R2 = 0.98). Practical applications Microencapsulation yield of sage extract in gelatin–pectin is 73.54 ± 2.04%. About 0.5% of sodium alginate permits the stabilization of microcapsules suspension. Sodium alginate and tragacanth had a better stabilizing effect compared with xanthan. After formulation, antioxidant activity of sage extract increases. After formulation, half‐life time of sage extract increases from 12.75 ± 1.95 to 258.64 ± 21.99 days.

show abstract

“…Among all microencapsulation preparation processes, complex coacervation is one of the most commonly used, which is achieved by interaction between two oppositely charged polymer solutions or colloids (McMullen et al 1982;Schmitt et al 1998Schmitt et al , 1999De Kruif et al 2004). …”

Section: Introductionmentioning

confidence: 99%

Spreadable dispersion of insect sex pheromone capsules, preparation via complex coacervation and release control of the encapsulated pheromone component molecule

Kong

Zhu

et al. 2008

Biomed Microdevices

View full text Add to dashboard Cite

Using insect female pheromone to disrupt their mating process is a new technology, which has been applied as environment friendly pesticides in agricultural and forestry industries to control pest infestation. Dodecanol (C(12)OH), as one of the simple pheromone component, was chosen and encapsulated as core material using gelatin (GE) and acacia gum (AG) as wall materials via complex coacervation. Through variations in capsule preparations, particularly the crosslinking density of the wall materials, release controllability of C(12)OH was studied. A series of C(12)OH-containing capsules were prepared with different concentrations of GE and AG and different crosslinkings. Crosslinking and C(12)OH encapsulation were enhanced when more crosslinker, either formaldehyde or glutaraldehyde, were used. At same level of crosslinker, lower crosslinking and higher C(12)OH encapsulation were obtained in microcapsules done with formaldehyde than those with glutaraldehyde. Constant release of C(12)OH was achieved in capsules prepared with glutaraldehyde. Mechanisms of C(12)OH release were discussed based on the results. Scanning electron microscopy was used to characterize the structure and morphology of the microcapsules, which seemingly confirmed existence of a core-shell structure in the capsules, with the coacervated polymers as the shell and C(12)OH the core.

show abstract

Pectin-Gelatin Complex Coacervates I: Determinants of Microglobule Size, Morphology, and Recovery as Water-Dispersible Powders

Cited by 42 publications

References 7 publications

Characterization of Sodium Carboxymethylcellulose-Gelatin Complex Coacervation by Viscosity, Turbidity and Coacervate Wet Weight and Volume Measurements

Characterization of Sodium Carboxymethylcellulose-Gelatin Complex Coacervation by Viscosity, Turbidity and Coacervate Wet Weight and Volume Measurements

Formulation of stable microcapsules suspensions contentSalvia officinalisextract for its antioxidant activity preservation

Spreadable dispersion of insect sex pheromone capsules, preparation via complex coacervation and release control of the encapsulated pheromone component molecule

Contact Info

Product

Resources

About