Pectin nanoparticles: Fabrication and uses

Ohlmaier-Delgadillo, Federico; Lizeth, Lara-Espinoza Claudia; Guadalupe, Félix-Arias K.; Zuleth, Gomeztagle-Romero M.; H., Gomez-Rodriguez Gabriel; Alfonso, Sánchez-Villegas J.; Rascón‐Chu, Agustín

doi:10.1016/b978-0-12-822351-2.00022-x

Cited by 3 publications

(2 citation statements)

References 135 publications

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“…It is derived from various plant sources, mainly apples, citrus fruits, and sugar beets, but algae, such as Spirulina maxima can also produce it. It is water-soluble, biodegradable, biocompatible, and non-toxic, making it a promising biomaterial for the preparation of nanocarrier systems for various therapeutic agents for biomedical applications [ 197 , 198 ]. Pectin-based nanoparticles are unique systems for targeted drug delivery in the colon because pectin is readily degraded in the colon while remaining chemically intact in the stomach and small intestine [ 199 ].…”

Section: Plant-based Biopolymeric Nanoparticles Used For Healthcare A...mentioning

confidence: 99%

Sustainable Biodegradable Biopolymer-Based Nanoparticles for Healthcare Applications

Kučuk

Primožič

Knez

et al. 2023

IJMS

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Biopolymeric nanoparticles are gaining importance as nanocarriers for various biomedical applications, enabling long-term and controlled release at the target site. Since they are promising delivery systems for various therapeutic agents and offer advantageous properties such as biodegradability, biocompatibility, non-toxicity, and stability compared to various toxic metal nanoparticles, we decided to provide an overview on this topic. Therefore, the review focuses on the use of biopolymeric nanoparticles of animal, plant, algal, fungal, and bacterial origin as a sustainable material for potential use as drug delivery systems. A particular focus is on the encapsulation of many different therapeutic agents categorized as bioactive compounds, drugs, antibiotics, and other antimicrobial agents, extracts, and essential oils into protein- and polysaccharide-based nanocarriers. These show promising benefits for human health, especially for successful antimicrobial and anticancer activity. The review article, divided into protein-based and polysaccharide-based biopolymeric nanoparticles and further according to the origin of the biopolymer, enables the reader to select the appropriate biopolymeric nanoparticles more easily for the incorporation of the desired component. The latest research results from the last five years in the field of the successful production of biopolymeric nanoparticles loaded with various therapeutic agents for healthcare applications are included in this review.

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Section: Plant-based Biopolymeric Nanoparticles Used For Healthcare A...mentioning

confidence: 99%

Sustainable Biodegradable Biopolymer-Based Nanoparticles for Healthcare Applications

Kučuk

Primožič

Knez

et al. 2023

IJMS

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“… Biopolymer-based structures for encapsulation of essential oils [ 37 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 ]. …”

Section: Biopolymer-based Structures For Formation Of Packaging Systemsmentioning

confidence: 99%

Insight on Incorporation of Essential Oils as Antimicrobial Substances in Biopolymer-Based Active Packaging

Tomić,

Šovljanski,

Erceg

2023

Antibiotics

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The increasing interest in microbiological food safety requires the development of sensitive and reliable analyses and technologies for preserving food products’ freshness and quality. Different types of packaging systems are one of the solutions for controlling microbiological activity in foods. During the last decades, the development of biopolymer-based active packaging with essential oil incorporation systems has resulted in technologies with exceptional application potential, primarily in the food industry. There is no doubt that this principle can facilitate food status monitoring, reduce food waste, extend the shelf life, improve the overall quality of food, or indicate a larger problem during the storage, production, and distribution of foodstuffs. On the other hand, most antimicrobial packaging systems are in the development phase, while the sensitivity, selectivity, complexity, and, above all, safety of these materials are just some of the essential questions that need to be answered before they can be widely used. The incorporation of essential oils as antimicrobial substances in biopolymer-based active packaging holds significant promise for enhancing food safety, extending shelf life, and offering more sustainable packaging solutions. While challenges exist, ongoing research and innovation in this field are likely to lead to the development of effective and environmentally friendly packaging systems with enhanced antimicrobial properties.

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