Peculiarities of Cardiovascular Risk Factors in Men Under 60 Years Old With Acute Kidney Injury During Myocardial Infarction

Sotnikov, A.V.; Гордиенко, А. В.; Nhan, T.V.; Thang, Nt; Rumyantseva, O.; Носович, Д В; Epifanov, S.Yu.

doi:10.26787/nydha-2686-6838-2020-22-4-120-127

Cited by 8 publications

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“…Однако при таком типе ожирения не учитывается функциональное состояние клеток жировой ткани. Также не проводится ультразвуковое измерение сосудистой стенки [7,8].…”

Section: оригинальные исследованияunclassified

Characteristics of the metabolic profile and the state of the vascular wall in men with metabolically neutral obesity

Sokolov¹,

Serdyukov²

2022

Russian Military Medical Academy Reports

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BACKGROUND: The prevalence of overweight in the Russian population is increasing every year. A diet with an excessive amount of easily digestible carbohydrates, low physical activity contribute to the rapid development of obesity at a young age. In Russia, 26% of the male population and 30% of women are overweight. When examining obese patients, the adipokine activity of adipose tissue is not taken into account in daily medical activities. The current concept of metabolically healthy obesity causes certain discussions in the scientific community due to diagnostic difficulties in stratifying overweight patients into metabolically healthy and unhealthy. AIM: was to characterize the lipid and carbohydrate profile, as well as to evaluate changes in the vascular wall in men with metabolically neutral obesity after a 34-year curation period. MATERIALS AND METHODS: The hospital therapy clinic analyzed the case histories of 93 patients aged 30 to 45 years. The study group of patients was examined twice: initially and 34-years after the initial examination. An anthropometric profile was examined in the designated sample of patients, a study of biochemical blood analysis was performed, and an assessment of the cardiovascular system was carried out. RESULTS: of the study showed that the metabolically neutral type is characterized by a low frequency of metabolic profile disorders, as well as parameters of the cardiovascular system. CONCLUSIONS: The probability of developing new cases of prediabetes, type 2 diabetes mellitus and initial atherosclerosis is maximal in patients with previously diagnosed insulin resistance and metabolically healthy obesity, minimal with normal body weight and in patients with metabolically neutral obesity.

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Section: оригинальные исследованияunclassified

Characteristics of the metabolic profile and the state of the vascular wall in men with metabolically neutral obesity

Sokolov¹,

Serdyukov²

2022

Russian Military Medical Academy Reports

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The Clinical Course of Myocardial Infarction Peculiarities in Men Under 60 Years Old With Acute Kidney Injury

Balabanov

Tupitcyn

Tassybayev

2021

Mediko-farmacevtičeskij žurnal "Pulʹs"

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Relevance. Acute kidneys injury (AKI) negatively affects the prognosis of myocardial infarction (MI). Aim. To evaluate MI clinical features (CF) in men under 60 years old (y.o.) with AKI during MI to improve prevention and outcomes. Material and methods. The study included men aged 19-60 years old with type I MI. Patients are divided into two age-comparable groups: I - the study group, with ACI - 25 patients; II - control, without it - 486 patients. A comparative assessment of the MI CF frequency in selected groups were performed. Results. In patients of the study group more often than in the control group, a combination of MI complications (64.0 and 36.9%; respectively; p = 0.009), psychic disorders (20.0 and 6.9%; p = 0.01), chronic heart failure (CHF) of the second functional class and above (NYHA) at the end of the eighth MI week (72.0 and 43.2%; p = 0.005), with a predominance of newly diagnosed CHF forms (36.0 and 28.0%; p = 0.006). In the study group, less often than in the control group, pulmonary hypertension was noted in the first 48 hours of MI (44.0 and 66.0%; p = 0.02) and at the end of the third MI week (38.1 and 60.3%; p = 0.04). Conclusions. There were no specific clinical signs of AKI in men under 60 y.o. with MI. At the same time, the study group has the worst prognosis during the observation period in terms of the frequency of MI complications combinations and CHF, which requires the start of prophylactic therapy from the moment of AKI verification.

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To the Question About Specific Features of the Cardiovascular Risk Factors Structure in Men Under 60 Years Old With Acute Kidney Injury During Myocardial Infarction

Гордиенко

Balabanov

Tassybayev

2021

Mediko-farmacevtičeskij žurnal "Pulʹs"

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Relevance. Acute kidney injury (AKI) worsens the prognosis of myocardial infarction (MI). Aim. To study the characteristics of cardiovascular (CVD) risk factors in men under 60 years of age with AKI in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I MI. Patients are divided into two age-comparable groups: I - the study group, with ACI - 25 patients; II - control, without it - 168 patients. A comparative analysis of the frequency of observation of the main and additional CVD risk factors in groups was performed. Results. In the patients of the study group, more often than in the control group, the following was observed: MI in winter (68.0 and 36.3%, respectively; p = 0.01), with repeated cases - the interval between infarction of more than one year (48.0 and 29.8%; p = 0.04); psychoemotional stress (64.0 and 46.1%; p = 0.04) or hypertensive crisis as a situation provoking MI (28.0 and 19.2%; p = 0.04); a history of: overweight less than 10 years (72.0 and 35.7%; p = 0.002) with moderate obesity (48.0 and 22.6%; p = 0.03), chronic heart failure (36.0 and 14.0%; p = 0.006), peptic ulcer (32.0 and 13.7%; p = 0.01), unstable angina (64.0 and 42.6%; p = 0.003), peripheral angiopathies (80.0 and 56.5%; p = 0.02), coronary angiography (45.5 and 25.5%; p = 0.04) and coronary artery bypass surgery (24.0 and 8.6%; p = 0.009). Conclusions. The structure of CVD risk factors in men under 60 years old with MI and AKI is characterized by the prevalence of moderate obesity, gastroduodenal ulcers, chronic heart failure, stress and crisis course of hypertension, coronary angiography and a history of coronary artery bypass surgery, as well as MI in winter. It is advisable to use the listed combinations of factors in predictive modeling and planning of preventive measures in such patients.

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Peculiarities of Cardiovascular Risk Factors in Men Under 60 Years Old With Acute Kidney Injury During Myocardial Infarction

Cited by 8 publications

References 0 publications

Characteristics of the metabolic profile and the state of the vascular wall in men with metabolically neutral obesity

Characteristics of the metabolic profile and the state of the vascular wall in men with metabolically neutral obesity

The Clinical Course of Myocardial Infarction Peculiarities in Men Under 60 Years Old With Acute Kidney Injury

To the Question About Specific Features of the Cardiovascular Risk Factors Structure in Men Under 60 Years Old With Acute Kidney Injury During Myocardial Infarction

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