Peculiarities of humoral antibacterial immunity in patients with psoriasis

Abstract

It is revealed that in patients with psoriasis the average indices of antibodies to eight of ten microbic antigens of normal microflora under study were significantly decreased in comparison with the indices of healthy persons. After the treatment the endotoxin level in blood was reduced by 10100 times but did not reach the standard. The results obtained show the essential role of humoral immunity state to endotoxine and the condition of pathogenic intestine microflora in the development and acute condition of psoriasis.