Peculiarities of local blood microcirculation in patients with psoriasis

Abstract

Local hemodynamic parameters were studied by means of laser Doppler flowmetry in 15 patients with psoriasis in the stationary stage, who have plaques on the inner surface of the forearm. LDF signals recorded at the site of psoriatic lesions of the tissue as well as in the intact tissue at a distance of 1-2 cm from the affected area were analysed. LDF signals were postprocessed by continuous wavelet transform using the Morlet wavelet.

A Multiparametric Approach to the Assessment of Cutaneous Microcirculation in Dermatological Patients (on the Example of Patients with Psoriasis)

“…Analyzing the data obtained by the LDF and VCS methods (Table 2) for the area of psoriatic lesion and uninvolved skin of the forearm, we can note that a typical pattern of microcirculatory disorders in psoriasis was observed at the first investigation stage, as described earlier [8][9][10][23][24][25][26][27]. The VCS recorded an increase in the density of the capillary network, and capillaries in a psoriatic plaque were broadened, twisted, and lengthened, compared with an intact tissue.…”

Studies of age-related changes in blood perfusion coherence using wearable blood perfusion sensor system

“…LDF is used for functional diagnostics of the blood microcirculation system, including diagnostics of socially significant diseases associated with the cardiovascular system, as well as their complications. [2][3][4] Furthermore, this method allows for the evaluation of the oscillatory processes in the microcirculatory bed. There are several frequency ranges that characterise the contribution of various factors to the LDF signal: endothelial (0.0095-0.021 Hz), neurogenic (0.021-0.052 Hz), myogenic (0.052-0.145 Hz), respiratory (0.145-0.6 Hz) and cardiac (0.6-2 Hz).…”