Abstract. The paper investigates threats to the relations between local industrial enterprises and consumer market retailers, as well as the place of chain structures in this sector of the economy. To achieve the objectives of the study, food industry and consumer market were analyzed statistically, and the activities of chain structures were researched in-field. It discovers the main trends of the regional consumer market, the impact of retail chains on the changes, and especially the effect of federal and international chains on the structure and development of the consumer market and on the way local manufacturers operate. Based hereon, the main focus areas of coordination and progress in regional-level enterprise-to-retail interaction have been identified as to ensure the economic security of the food industry and the region as a whole.