Pediatric bladder neuroblastoma: Case report and literature review

Abstract

Neuroblastoma (NBL) of the urinary bladder is an extremely rare diagnosis, with only 6 cases reported in the literature to date. We report the case of a 3-year-old boy who presented with gross hematuria, and was diagnosed with bladder NBL after partial cystectomy. Two-year follow-up has been unremarkable. This case highlights a rare neoplasm of the urinary bladder in a pediatric patient.

Neuroblastoma of the Urinary Bladder in an Infant

“…Six patients were under 15 months of age, 12 whereas the other two patients were 3 and 5 years of age, respectively. 13 14 Interestingly, in six out of eight reported cases, the masses originated from the dome of the UB. 12 13 14 The two other reported sites of pathology were the lateral and the anterior walls of the UB.…”

“…12 13 14 The two other reported sites of pathology were the lateral and the anterior walls of the UB. 12 13 14 All pathological subtypes of the NBL spectrum were described with four patients exhibiting poorly differentiating NBL, one case of stroma-poor differentiating NBL, one ganglioneuroblastoma (GNBL), a single ganglioneuroma (GN) and one case was not specified. 12 13 14…”