Pediatric giant cell granuloma of the temporal bone: a case report and brief review of the literature

Sharma, Rewati Raman; Verma, Ashok; Pawar, Sanjay J.; Dev, Ebenezer J.; Devadas, R.; Shiv, V. K.; Musa, Mohammed M.

doi:10.1054/jocn.2001.1046

Cited by 20 publications

(20 citation statements)

References 9 publications

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“…Also, vivid enhancement is seen after intra venous gadolinium chelate administration. A more cystic multiloculated appearance has been reported as well (15)(16)(17)(18).…”

Section: Discussionmentioning

confidence: 79%

Unilateral giant cell lesion of the jaw in Noonan syndrome

Eyselbergs

Vanhoenacker

Hintjens

et al. 2014

Journal of the Belgian Society of Radiology

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noonan syndrome (ns) is an etiologically heterogeneous disorder caused by mutations in the ras-maPK signaling pathway. noonan-like/multiple giant Cell lesion (nl/mgCl) syndrome is initially described as the occurrence of multiple gnathic giant cell lesions in patients with phenotypic features of ns. nowadays, ns/mgCl syndrome is considered a variant of the ns spectrum rather than a distinct entity. we report the case of a 14-year-old female patient carrying a SOS1 mutation with a unilateral giant cell lesion of the right mandible. Cross-sectional imaging such as Ct and mri are not specific for the diagnosis of oral giant cell lesions. nonetheless, intralesional scattered foci of low si on t2-wi, corresponding to hemosiderin deposits due to hemorrhage, can help the radiologist in narrowing down the differential diagnosis of gnathic lesions in patients with ns. Key-word: jaws.From: 1.

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“…Also, vivid enhancement is seen after intra venous gadolinium chelate administration. A more cystic multiloculated appearance has been reported as well (15)(16)(17)(18).…”

Section: Discussionmentioning

confidence: 79%

Unilateral giant cell lesion of the jaw in Noonan syndrome

Eyselbergs

Vanhoenacker

Hintjens

et al. 2014

Journal of the Belgian Society of Radiology

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“…6 In contrast, malignancy and metastasis have never been reported in cases of giant cell reparative granuloma. 6,9,15 Differentiation of giant cell reparative granuloma from giant cell tumour is important, given the latter's far worse prognosis. 4,9 On histological examination, the typical appearance of giant cell tumour is of larger multinucleated giant cells within a background of mononuclear giant cells, with the latter commonly containing mitotic figures.…”

Section: Discussionmentioning

confidence: 99%

Giant cell reparative granuloma of the temporal bone successfully resected with preservation of hearing

et al. 2013

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“…In our case, the progressive head tumor mass developed immediately after the head injury that was sustained at a young age, and the relationship between tumor onset and external injury was unclear. In some cases, skull tumor-like lesions reportedly started growing after external injuries [6, 7], but there have been no reported cases of FD triggered by head injury. Therefore, in the preoperative differential diagnosis with the images shown above, eosinophilic granuloma with cystic change was strongly suspected, rather than FD.…”

Section: Discussionmentioning

confidence: 99%

Posttraumatic Cranial Cystic Fibrous Dysplasia

Tomiyama

Aoki

Nakayama

et al. 2011

Case Reports in Medicine

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A 14-year-old was girl admitted to our hospital with a subcutaneous mass of the occipital head. The mass had grown for 6 years, after she had sustained a head injury at the age of 6, and was located directly under a previous wound. Skull X-ray Photograph (xp), computed tomography (CT), and magnetic resonance imaging (MRI) showed a bony defect and cystic changes in the skull corresponding to a subcutaneous mass. Bone scintigraphy revealed partial accumulation. The patient underwent total removal of the skull mass, and the diagnosis from the pathological findings of the cyst wall was fibrous dysplasia (FD). The radiographic findings for cystic cranial FD can be various. Progressive skull disease has been reported to be associated with head trauma, but the relationship between cranial FD and head trauma has not been previously reported. Previous studies have suggested that c-fos gene expression is a key mechanism in injury-induced FD.

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Pediatric giant cell granuloma of the temporal bone: a case report and brief review of the literature

Cited by 20 publications

References 9 publications

Unilateral giant cell lesion of the jaw in Noonan syndrome

Unilateral giant cell lesion of the jaw in Noonan syndrome

Giant cell reparative granuloma of the temporal bone successfully resected with preservation of hearing

Posttraumatic Cranial Cystic Fibrous Dysplasia

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