Pediatric Graves’ Disease

Bansal, Shipra; Umpaichitra, Vatcharapan; Desai, Ninad; Pérez, Sheila; Perez-Colon, Sheila

doi:10.16966/2380-548x.104

Cited by 3 publications

(1 citation statement)

References 74 publications

(108 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The demographic features were similar to findings from previous studies .6,7,17-18 The observed female-tomale ratio of 3:1 and mean age of 12.02±4.85 years compared favourably to reported data from other studies, which showed female-to-male ratios ranging from 4:1 to 6:1 and a mean age of 10-15 years. 6,7,9,[11][12][13][14][15][16][17][18] The majority of the patients presented as typical cases of GD; therefore, diagnosis was based on the clinical presentations and biochemical blood test )TSH, FT4, FT3( results. Thyroid antibodies, including TSI and TRAb, were not tested due to the unavailability of these tests.…”

mentioning

confidence: 99%

The characteristics of Grave’s disease in children and adolescent patients in Al-Madinah Al-Munawwarah

Alradadi¹,

Omar²,

Alhusayni³

et al. 2023

SMJ

View full text Add to dashboard Cite

‫أكثر‬ ‫كانت‬ ‫اإلناث.‬ ‫من‬ )75.9%( 44 ‫منهم‬ ‫عام،‬ 12.02±4.85 ،)60.3%( ‫الرقبة‬ ‫تورم‬ ،)63.8%( ‫اجلحوظ‬ ً ‫شيوعا‬ ‫السريرية‬ ‫العالمات‬ ‫والصلع‬ )1.72%( ‫البهاق‬ ‫كان‬ .)29.3%( ‫والرعشة‬ ،)46.6%( ‫اخلفقان‬ ‫قيمة‬ ‫كانت‬ ‫مرضانا.‬ ‫في‬ ‫لوحظت‬ ‫التي‬ ‫املناعية‬ ‫األمراض‬ ‫من‬ )1.72%( ‫الغدة‬ ‫حتفيز‬ ‫لهرمون‬ )IQR) 0.01 )0.36) )ulU / mL) ‫الوسيط‬ ‫حيث‬ ‫من‬ .FT4 ‫لـ‬ )pmol / L) )29.50) 24.89 ‫و‬ )TSH) ‫الدرقية‬ 6 ‫وخضع‬ ‫الدرقية،‬ ‫للغدة‬ ‫مضادة‬ ‫أدوية‬ )94.8%) 54 ‫تلقى‬ ‫العالج،‬ ‫طرق‬ ‫باليود‬ ‫عولج‬ )1.72%( ‫واحد‬ ‫ومريض‬ ‫الدرقية‬ ‫الغدة‬ ‫الستئصال‬ )10.3%( ‫املشع.‬

show abstract

mentioning

confidence: 99%

The characteristics of Grave’s disease in children and adolescent patients in Al-Madinah Al-Munawwarah

Alradadi¹,

Omar²,

Alhusayni³

et al. 2023

SMJ

View full text Add to dashboard Cite

show abstract

Skin Sceneries of Thyroid Disorders and Impact of Thyroid on Different Skin Diseases: A Scoping Review Focused on Pediatric Patients

Cammisa,

Zona,

Guerriero

et al. 2024

Children

View full text Add to dashboard Cite

Thyroid function plays a seminal role in the growth and development of children, and alterations in signaling pathways which interfere with the biosynthesis, transport, and metabolism of thyroid hormones might impact on the skin of such patients: this review explores the relationship between different thyroid disorders and dermatological manifestations with a particular focus on the pediatric population. Common cutaneous conditions associated with thyroid dysfunction may include chronic urticaria, vitiligo, and alopecia, which can be early harbingers of an underlying endocrine disruption. This review also highlights the growing cognizance of a “thyroid–skin axis”, with thyroid hormones influencing many physiologic processes within the skin such as keratinocyte proliferation, hair growth, and epidermal differentiation. A precocious recognition of abnormal dermatological signs can be crucial in pediatric patients for a timely diagnosis before any development of complications and for personalized treatments of an underlying thyroid disorder, which can even be symptomless at an initial phase. Despite the lack of standardized guidelines for managing dermatologic manifestations occurring in thyroid diseases, a regular screening to identify endocrine dysfunction is recommended in those children who present chronic urticaria, vitiligo, or alopecia, though further research is needed to decipher mechanisms involved in the thyroid-skin partnership and develop more targeted management approaches.

show abstract

Nuclear Medicine in the Assessment of Thyrotoxicosis Associated with Increased Thyroid Function and Radioiodine 131 Ablative Therapies

Muñoz¹

2019

Thyroid Disorders

View full text Add to dashboard Cite

Nuclear medicine is directly involved in both the diagnosis and treatment of benign thyroid disease. Thyroid scintigraphy (most commonly with technetium-99 m pertechnetate) should be used as the imaging modality of choice for assessment of thyrotoxicosis, since it demonstrates the functional state of the thyroid gland. An adequate understanding of the pathophysiological mechanisms and characteristics of the patient is essential, as well as the different treatments of thyroid disorders that present with hyperthyroidism (Graves' disease, toxic multinodular goiter, and toxic adenoma-Plummer's disease). Therapeutic modalities include antithyroid drugs, radioiodine and surgery. Antithyroid drugs are the first line of therapy and regarding the use of radioiodine, current recommendations consider it a safe and effective therapeutic alternative in hyperthyroidism. Finally, we highlight the existence of some special situations (children, pregnancy, thyroid eye disease, chronic renal failure and dialysis patients) and the importance of radiation protection measures to the patient, the public and professionals.

show abstract

Pediatric Graves’ Disease

Cited by 3 publications

References 74 publications

The characteristics of Grave’s disease in children and adolescent patients in Al-Madinah Al-Munawwarah

The characteristics of Grave’s disease in children and adolescent patients in Al-Madinah Al-Munawwarah

Skin Sceneries of Thyroid Disorders and Impact of Thyroid on Different Skin Diseases: A Scoping Review Focused on Pediatric Patients

Nuclear Medicine in the Assessment of Thyrotoxicosis Associated with Increased Thyroid Function and Radioiodine 131 Ablative Therapies

Contact Info

Product

Resources

About