Pediatric Multidrug-resistant Tuberculosis in Kyiv City, Ukraine

Chiang, Silvia S.; Sheremeta, Yana; Padilla, Rachel Sophie; Jenkins, Helen E.; Horsburgh, C. Robert; Петренко, В.І.; Rybak, Natasha

doi:10.2991/jegh.k.190225.002

Cited by 2 publications

(3 citation statements)

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“… 2 In most settings, isolation occurs at home, while in former Soviet republics, patients with TB disease are isolated in TB hospitals. 3–5 …”

Section: Introductionmentioning

confidence: 99%

“…2 In most settings, isolation occurs at home, while in former Soviet republics, patients with TB disease are isolated in TB hospitals. [3][4][5] Few reports have described the impact of prolonged isolation, which we define as lasting 1 month or more, on adolescents with TB. 6 Adolescents may be particularly vulnerable to the negative effects of prolonged isolation.…”

Section: Introductionmentioning

confidence: 99%

“…Other MOHs require longer isolation periods and/or multiple sputum smears that are negative for acid-fast bacilli (AFB) 2. In most settings, isolation occurs at home, while in former Soviet republics, patients with TB disease are isolated in TB hospitals 3–5…”

Section: Introductionmentioning

confidence: 99%

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Impact of prolonged isolation on adolescents with drug-susceptible tuberculosis in Lima, Peru: a qualitative study

et al. 2022

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ObjectivesPatients with tuberculosis (TB) generally are instructed to isolate at the beginning of treatment in order to prevent disease transmission. The duration of isolation varies and may be prolonged (ie, lasting 1 month or more). Few studies have examined the impact of isolation during TB treatment on adolescents, who may be more vulnerable to its negative effects.MethodsThis study took place from 2018 through 2019 in Lima, Peru, where the Ministry of Health mandates the exclusion of patients with TB from educational institutions for at least 2 months. Using semi-structured guides, we conducted individual in-depth interviews with adolescents who received treatment for drug-susceptible TB, their primary caregivers and health providers. We performed thematic analysis of the transcribed interviews.ResultsWe interviewed 85 participants: 34 adolescents, 36 caregivers and 15 healthcare workers. At the time of their TB diagnoses, 28 adolescents were in secondary, postsecondary, vocational or military school. Adolescents with drug-susceptible TB were prescribed home isolation usually for 2 (and occasionally for 1) months. Consequently, they could neither attend school nor socialise with family members or friends. Two primary themes emerged from the interviews. First, as a result of their exclusion from school, most adolescents fell behind academically and had to repeat a semester or academic year. Second, absence from school, separation from friends and loved ones, and reinforcement of TB-related stigma (arising from fear of TB transmission) harmed adolescents’ mental health.ConclusionProlonged isolation led to educational setbacks and emotional trauma among adolescents with TB. Prolonged isolation is not supported by current evidence on TB transmission and is problematic from a human rights perspective, as it violates adolescents’ rights to education and freedom of movement. Isolation recommendations should be re-evaluated to align with data on TB transmission and the principles of patient-centred care.

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“… 2 In most settings, isolation occurs at home, while in former Soviet republics, patients with TB disease are isolated in TB hospitals. 3–5 …”

Section: Introductionmentioning

confidence: 99%