Pediatric Oral Food Challenge Outcomes by Food Type in a Large Pediatric Allergy Clinic

Gupta, Shikha; Robinson, Melissa L.; Lanser, Bruce J.

doi:10.1016/j.jaci.2018.12.514

Cited by 1 publication

(11 citation statements)

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“…An IgE-mediated food allergy is defined as a reproducible adverse reaction after exposure to a specific antibody, IgE, which triggers an immune response to a specific food 8 . It is possible for individuals to produce detectible IgE without clinical symptoms.…”

Section: What Are the Defining Characteristics Of Ige-mediated Allergy?mentioning

confidence: 99%

“…Another factor that sets these symptoms apart from other adverse food reactions is that they are reproducible upon every exposure to the offending food. However, it is important to note that reaction timing, symptom severity, and even the sequence of symptom development can vary widely even for the same individual 8 …”

Section: Signs and Symptoms: Triggers Timing Reproducibility And Spec...mentioning

confidence: 99%

“…Although symptoms may appear obvious during some reactions, they may equally seem minor and less obvious during others. Cutaneous symptoms such as hives or swelling are present in most reactions; however, they are not present in approximately 20% of anaphylactic reactions 8,24 . IgE-mediated food allergy are rapid, reproducible with every ingestion of the allergen, and have the potential to progress to anaphylaxis.…”

Section: Signs and Symptoms: Triggers Timing Reproducibility And Spec...mentioning

confidence: 99%

“…Abbreviations: IgE, immunoglobulin E; IgE FA, IgE-mediated food allergy; NSAID, nonsteroidal anti-inflammatory drug.Data were derived from Gupta, 8 Sampson et al, 9 the National Academy of Sciences, Engineering, and Medicine, 17 Varshney and Pongracic, 24 Nguyen and Heath 27 a Also called oral allergy syndrome. b Potentially anaphylactic.…”

Section: How Is Ige-mediated Food Allergy Diagnosed?mentioning

confidence: 99%

“…Data were derived from Gupta, 8 Sampson et al, 9 the National Academy of Sciences, Engineering, and Medicine, 17 Varshney and Pongracic, 24 Nguyen and Heath 27 …”

Section: How Is Ige-mediated Food Allergy Diagnosed?mentioning

confidence: 99%

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Immunoglobulin E–Mediated Food Allergies

Weston,

Myers

2023

Nutr Today

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This second article on food allergies focuses on food allergic reactions involving specific immunoglobulin E (IgE) mechanism within the immune system. An IgE-mediated food allergy diagnosis requires both the sensitization (positive test) and the clinical signs and symptoms consistent with IgE-mediated food allergy response. Having the confirmed diagnosis and management plan is crucial because the signs and symptoms appear rapidly after every ingestion of a food with the potential to progress in severity to a life-threatening situation, anaphylaxis. A clear understanding of what constitutes a food allergy, specifically an IgE-mediated food allergy, will facilitate clear communication among healthcare professionals, patients and caregivers, and those in the public.

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Section: What Are the Defining Characteristics Of Ige-mediated Allergy?mentioning

confidence: 99%

Section: Signs and Symptoms: Triggers Timing Reproducibility And Spec...mentioning

confidence: 99%

Section: Signs and Symptoms: Triggers Timing Reproducibility And Spec...mentioning

confidence: 99%

Section: How Is Ige-mediated Food Allergy Diagnosed?mentioning

confidence: 99%

“…Data were derived from Gupta, 8 Sampson et al, 9 the National Academy of Sciences, Engineering, and Medicine, 17 Varshney and Pongracic, 24 Nguyen and Heath 27 …”

Section: How Is Ige-mediated Food Allergy Diagnosed?mentioning

confidence: 99%

See 3 more Smart Citations