Pediatric patients with type 1-diabetes: growth and growth failure associated factors

Growth status of Adolescents with Diabetic Type 1 and its associated factors

“…[13] Similarly, Khadikar et al [23] concluded that 27.1% of diabetic children were stunted, but much lower prevalence of stunted growth of 15% was reported by AL-Rubaee, [18] and of 13.1% by Abed et al [25] These different results could be due to the wider age cohorts considered, as we studied only adolescents. In the study we reported that more than half of diabetic adolescents were within underweight (BMI-for-age); the same result was reported by Zurita et al [26] about pediatric patients with T1DM, whom they noted had growth and growth failure associated factors manifest in half of participants having impaired growth. A lower rate of 33.1% of diabetic children were underweight in the study of Kayirangwa [22] , and descending BMI-for-age scores of 19.4% [18] and 13.2% [23] were reported by other studies.…”

Insulin-like growth factor 1 and sex hormones for assessment of anthropometric and pubertal growth of Egyptian children and adolescents with type 1 diabetes mellitus (single center study)

“…In our study, we found that short stature in diabetic patients was significantly related to higher HbA1C compared to those with normal stature. In agreement with Zurita-Cruz et al ., who reported in their study that HbA1c and poor glycemic control were lower in patients with normal growth parameters compared to those with growth alterations [ 21 ]. On the other hand, several studies found that there was no significant correlation between metabolic control and linear growth in diabetic boys or girls.…”

“…Meanwhile, Zurita-Cruz et al . reported that 50% of their patients were prepubertal, and only 5% had reached a Tanner stage 4 [ 21 ]. Similarly, another study carried on 206 adolescents with T1DM, showed significant impairment in pubertal growth with height SDS reduction [ 47 ].…”