Pediatric primary and metastatic neuroblastoma: MRI findings

Nour-Eldin, Nour-Eldin A.; Abdelmonem, Ola; Tawfik, Ahmed; Naguib, N; Klingebiel, Thomas; Rolle, Udo; Schwabe, Dirk; Harth, Marc; Eltoukhy, Mohammed M.; Vogl, Thomas J.

doi:10.1016/j.mri.2012.02.028

Cited by 26 publications

(12 citation statements)

References 27 publications

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“…MRI has a unique soft tissue contrast, and therefore anatomical localization of lesions with MRI is very well possible. Furthermore MRI might provide early detection of bone marrow infiltration by the tumor before osseous destruction becomes apparent on radiography or CT or before metabolic changes occur on bone scintigraphy or PET-CT [56][57][58]. However, in children, in contrast to adults, it can be difficult to differentiate highly cellular hematopoietic marrow (red marrow) from metastatic disease [59].…”

Section: Discussionmentioning

confidence: 99%

A Systematic Literature Review of Imaging Definitions for Detection of Bone and Bone Marrow Metastases in Neuroblastoma Patients

Bleeker¹,

Heijkoop²,

Dalen³

et al. 2015

J Bone Marrow Res

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Objective: The presence of bone and bone marrow (BM) metastases in neuroblastoma patients are independent adverse prognostic factors, so precise and consistent definitions of both categories on imaging are important. The objectives of this systematic review were to identify all definitions reported for detection of bone and bone marrow metastases on imaging in neuroblastoma to determine diagnostic accuracies of the most frequently used definitions for detection of bone and/or BM metastases on each imaging technique. Methods: We searched MEDLINE/PubMed (1945 to April 2013) and EMBASE/Ovid (1980 to April 2013). Full-text original studies were included if they reported definitions of bone and/or BM metastases on diagnostic imaging of children with suspected metastatic neuroblastoma. As reference standard for bone metastases bone scintigraphy was used and for bone marrow metastases bone marrow biopsies/aspirates. Methodological quality was assessed. Results: Of 403 identified studies (plus one relevant reference), 131 were assessed in full-text and 31 finally included, 23 described BM metastases and 18 bone metastases. No uniform definitions of bone and bone marrow metastases were reported for each imaging method. On MIBG scintigraphy bone metastases were mostly defined as "focal" and BM metastases as "diffuse" and on MRI both definitions were used for BM metastases. The diagnostic accuracy of different diagnostic methods to detect bone (reference test bone scintigraphy) or BM (reference test bone marrow biopsies/ trephines) metastases varied widely. Conclusion: No uniform definitions of bone and bone marrow metastases were reported for each imaging method and concerning the diagnostic accuracy no general conclusions could be drawn.

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Section: Discussionmentioning

confidence: 99%

A Systematic Literature Review of Imaging Definitions for Detection of Bone and Bone Marrow Metastases in Neuroblastoma Patients

Bleeker¹,

Heijkoop²,

Dalen³

et al. 2015

J Bone Marrow Res

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“…Magnetic Resonance Imaging : Magnetic resonance imaging is an important imaging modality of choice because it does not utilize radiation and provides high contrast resolution for the detection, multiplanar localization, and assessment of the extent of primary tumor involvement [ 33 ]. It is superior to CT to assess marrow infi ltration and intraspinal extension.…”

Section: Imaging Featuresmentioning

confidence: 99%

Tumors of the Adrenal Gland

Kao

Pinto-Rojas

2014

Pediatric Malignancies: Pathology and Imaging

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“…Нейробластома (НБ) -злокачественная солидная опухоль, характерная для детского возраста, развивается из эмбриональных клеток-предшественников симпатической нервной системы, составляет около 7-8 % всех злокачественных новообразований в детской популяции и в 95 % случаев развивается в возрасте до 5 лет [1][2][3]. Наиболее частая локализация НБ -это область надпочечников (35-40 %), паравертебральные нервные ганглии забрюшинного пространства (30-35 %) и средостения (16-20 %), реже опухоль поражает область шеи (2-3 %) и малого таза (1-3 %) [4][5][6].…”

Section: Introductionunclassified

Image defined risk factors in patients with neuroblastoma. Literature review

Терновая

Качанов

Шаманская

et al. 2019

Ross. ž. det. gematol. onkol.

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Currently, two staging systems are used: the International Neuroblastoma Staging System (INSS), which relies on surgical staging, and the International Neroblastoma Risk Group Stading System (INRGSS), which relies on preoperative imaging for staging and image-defined risk. The article presents a review of the literature on image defined risk factors (IDRF) determined during radiological studies (computed tomography and magnetic resonance imaging) in patients with neuroblastoma. The article focuses on the definition of IDRFs, their prevalence and their influence on surgical outcomes and prognosis of patients with neuroblastoma.

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Pediatric primary and metastatic neuroblastoma: MRI findings

Cited by 26 publications

References 27 publications

A Systematic Literature Review of Imaging Definitions for Detection of Bone and Bone Marrow Metastases in Neuroblastoma Patients

A Systematic Literature Review of Imaging Definitions for Detection of Bone and Bone Marrow Metastases in Neuroblastoma Patients

Tumors of the Adrenal Gland

Image defined risk factors in patients with neuroblastoma. Literature review

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