Pediatric reference intervals of liver and renal function tests from birth to adolescence in Chinese children as performed on the Olympus AU5400

Liu, Junjie; Dai, Yanpeng; Lee, Yushan; Yuan, Enwu; Wang, Quanxian; Wang, Linkai; Su, Yanhua

doi:10.1016/j.cca.2019.01.001

Cited by 20 publications

(39 citation statements)

References 11 publications

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“…ULs of Ca, Mg, Fe, TCHO and HDL-C are signi cantly lower than those from the experiment based on the cord blood in Korean [17]. The RIs of most analytes are similar to those from the study in Lanzhou, China [18], however the RIs of liver enzymes except CHE showed great differences compared with those from Zhengzhou, China [19].…”

Section: Ris Comparison To Other Studiessupporting

confidence: 53%

“…Compared to another two studies in other parts of China, there might be some factors that contributed to the differences between RIs, including actual differences between cities, laboratories, analytical systems and statistical calculation methods reported in these studies. Moreover, Liu et al [19]. used an indirect method for determination of RIs, which based on the stricter exclusion criteria and wider age intervals, and then little data about the rapid changes was presented during the rst days.…”

Section: Comparison To Other Studiesmentioning

confidence: 99%

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Reference Intervals for 26 Common Biochemical Analytes in Term Neonates in Jilin Province, China

Wang

Zhu

Zhou

et al. 2020

Preprint

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Background: Biochemical analytes provide information for neonatal disease management and therapy, and population-based reference intervals (RIs) are essential to accurately interpret laboratory test results. This study aimed to establish local RIs for biochemical assays in term neonates.Methods: A total of 195 healthy term neonates from birth to 3rd day were recruited as reference individuals prospectively. Analytes of 26 common biochemistries were measured using the VITROS 5600 Integrated System. The 3-level nested ANOVA was performed to assess the need for partitioning RIs of each analytes, and RIs were derived by a nonparametric method or robust method. Multiple regression analysis was used to evaluate specific correlations between the analytes and individual characteristics including age, gender, gestational age, birthweight and delivery mode.Results: There were no between-sex differences in all analytes, whereas there were significant between-day-age differences in 6 analytes. Small between-delivery-mode differences were observed in the results for potassium, phosphate, and urea. The major related factor of most analytes was postnatal age. During the first 3 days, values of iron, lipids and lipoproteins increased; creatinine, urea, uric acid, creatine kinase and lactate dehydrogenase decreased; other analytes showed slight changes or relatively stable trends. Reference limits of some analytes, particularly lactate dehydrogenase and alkaline phosphatase, were significant different from adult and pediatric groups.Conclusions: RIs of 26 common biochemical analytes are established for term neonates aged 0 to 3 days in northeast China. Additionally, it is suggested that age-related changes should be valued in the clinical decision-making process for newborns.

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Section: Ris Comparison To Other Studiessupporting

confidence: 53%

Section: Comparison To Other Studiesmentioning

confidence: 99%

Reference Intervals for 26 Common Biochemical Analytes in Term Neonates in Jilin Province, China

Wang

Zhu

Zhou

et al. 2020

Preprint

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“…For Creatinine, both lower and upper limit reference values were comparable to several western and African studies [6,13,[16][17][18][19]] except a study from South West Ethiopia [20] where higher upper limit value was reported. In all studies females had less upper limit reference value than males.…”

Section: Plos Onesupporting

confidence: 78%

“…The upper limit of most clinical chemistry parameters among apparently healthy individuals in Africa are higher relative to Taiwan [15], Canada [13] and China [16].This difference may be due to genetic makeup, living style and altitude. The manufacturers' reference interval provided in the leaflets of the reagents used in the current study presented a single RI range for both sexes except for ALP and creatinine.…”

Section: Plos Onementioning

confidence: 99%

“…Southwest Ethiopia [6,13,[15][16][17][18][19][20].This difference may be due to sample size (in china for example 2683 males and 2292 females were participated) or specimen collection time difference (In Taita Kenya, collection was performed at day time). The Total and Direct Bilirubin reference limits in the current study were consistent with reference limit values conducted in Canada, China, Taita Kenya, Zimbabwe [6,13,16,19] except the upper limit value of direct bilirubin in Zimbabwae [6] which is low. In contrast, the current upper limit provided was lower than those reported from west Kenya, Meru Kenya, and Southwest Ethiopia [17,18,20].…”

Section: Plos Onementioning

confidence: 99%

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Community based reference interval of selected clinical chemistry parameters among apparently healthy Adolescents in Mekelle City, Tigrai, Northern Ethiopia

et al. 2020

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Background Locally established clinical laboratory reference intervals (RIs) are required to interpret laboratory test results for screening, diagnosis and prognosis. The objective of this study was establishing reference interval of clinical chemistry parameters among apparently healthy adolescents aged between 12 and 17 years in Mekelle, Tigrai, northern part of Ethiopia. Methods Community based cross sectional study was employed from December 2018 to March 2019 in Mekelle city among 172 males and 172 females based on Multi stage sampling technique. Blood samples were tested for Fasting blood sugar (FBS), alanine aminino transferase (ALT), aspartate amino transferase (AST), alkaline phosphatase (ALP), Creatinine, urea, total protein, albumin (ALB), direct and indirect bilirubin (BIL.D and BIL.T) using 25 Bio system clinical chemistry analyzer. Results were analyzed using SPSS version 23 software and based on the Clinical Laboratory Standard Institute (CLSI)/ International Federation of Clinical Chemistry (IFCC) C 28-A3 Guideline which defines the reference interval as the 95% central range of 2.5 th and 97.5 th percentiles. Mann Whitney U test, descriptive statistics and box and whisker were statistical tools used for analysis.

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Establishment of age‐ and sex‐specific reference intervals for serum liver function tests in pediatric population aged 1–<18 years: A prospective study

Zhu

Wang

Zhou

et al. 2021

Clinical Laboratory Analysis

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Pediatric reference intervals of liver and renal function tests from birth to adolescence in Chinese children as performed on the Olympus AU5400

Cited by 20 publications

References 11 publications

Reference Intervals for 26 Common Biochemical Analytes in Term Neonates in Jilin Province, China

Reference Intervals for 26 Common Biochemical Analytes in Term Neonates in Jilin Province, China

Community based reference interval of selected clinical chemistry parameters among apparently healthy Adolescents in Mekelle City, Tigrai, Northern Ethiopia

Establishment of age‐ and sex‐specific reference intervals for serum liver function tests in pediatric population aged 1–<18 years: A prospective study

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