Pediatric Soft-Tissue Tumors

Aflatoon, Kamran; Aboulafia, Albert J.; McCarthy, Edward F.; Frassica, Frank J.; Levine, Alan M.

doi:10.5435/00124635-200309000-00006

Cited by 16 publications

(10 citation statements)

References 56 publications

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“…It can be specific in identifying soft-tissue tumors based on the amount of fat and fibrous tissue ( 4 ). Fibrous tissue is hypointense compared to muscle on T1W and T2W images, myxoid tissue has low signal on T1W images and high signal on T2W images, and fat is hyperintense on T1W and T2W images ( 5 ). Characteristically, FHI has low signal on T1W images and heterogeneous signal on T2W images on MRI, with fibrous trabeculae interspersing with fat in an organized pattern in the subcutaneous tissue–which is pathognomonic of FHI ( 4 , 5 , 6 ).…”

Section: Discussionmentioning

confidence: 99%

Precalcaneal congenital soft-tissue lesions in children: A case report of fibrous hamartoma of infancy and an approach to differential diagnosis

Choudhary¹,

Adapa²

2010

Radiology Case Reports

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Precalcaneal soft-tissue lesions are uncommon in the pediatric population and can present a diagnostic challenge. Fibrous hamartoma of infancy (FHI) is relatively rare in this location. We report an interesting case of FHI in a 3-years-and-10-months-old boy in the precalcaneal location that was present since birth. We describe the imaging findings of FHI on X-ray, ultrasound, and MRI and discuss the differential diagnoses. It is important to consider FHI during differential diagnosis and be aware of the imaging features of other common possible diagnoses in the precalcaneal region for appropriate management.

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Section: Discussionmentioning

confidence: 99%

Precalcaneal congenital soft-tissue lesions in children: A case report of fibrous hamartoma of infancy and an approach to differential diagnosis

Choudhary¹,

Adapa²

2010

Radiology Case Reports

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“…Ultrasonography (US) (both gray-scale and Doppler) is the modality of choice for small, superficial lesions (infantile hemangioma, vascular malformation, pilomatricoma, synovial cyst) or when the clinical history strongly suggests a specific diagnosis (fibromatosis colli, abscess, hematoma, lymphadenitis) (1,2). Conventional radiography may prove useful in selected cases by revealing the osseous origin of a palpable mass, showing bone invasion or deformity from an adjacent softtissue mass, helping evaluate myositis ossificans, or demonstrating soft-tissue calcifications such as phleboliths (2,3). The role of computed tomography is now mainly limited to the evaluation of myositis ossificans.…”

Section: Clinical Evaluation and Imaging Approachmentioning

confidence: 98%

“…Vascular lesions represent the most common cause of pediatric soft-tissue masses (1,3). The most widely accepted classification system for vascular lesions is the one developed by Mulliken and Glowacki (30), which divides these lesions into two distinct groups: hemangiomas and vascular malformations.…”

Section: Vascular Lesionsmentioning

confidence: 99%

Pediatric Soft-Tissue Tumors and Pseudo-tumors: MR Imaging Features with Pathologic Correlation

Navarro¹,

Laffan²,

Ngan³

2009

RadioGraphics

163

126

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A wide spectrum of entities may give rise to soft-tissue masses in children, including benign and malignant tumors, pseudotumors, and both neoplastic and nonneoplastic vascular lesions. Because of its excellent tissue contrast, multiplanar capability, and lack of ionizing radiation, magnetic resonance (MR) imaging has become the modality of choice in the evaluation of deep and large soft-tissue masses in children. In the vast majority of cases, however, accurate interpretation of the MR imaging findings requires correlation with the clinical findings. For example, in most posttraumatic and inflammatory pseudotumors, the clinical history is fundamental to establishing the diagnosis. In the evaluation of periarticular cysts, the location of the mass and its relationship to a joint are crucial for diagnosis, whereas in the evaluation of vascular lesions, including hemangiomas and vascular malformations, clinical findings combined with MR imaging findings are needed for accurate diagnosis in most cases. The identification of fat within adipocytic tumors is useful, but tissue biopsy may be required for final diagnosis. Nevertheless, MR imaging is useful in determining the origin and character of pediatric soft-tissue masses, defining their extent and their relationship to adjacent structures, and performing posttherapy follow-up.

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“…1,2 In a series of more than 900 benign and malignant soft tissue tumours detected in the first two decades of life, 30 % were of vascular origin. 3 Estimates of the overall prevalence of vascular anomalies range from 6 % to 25 %. 4 The most frequent location is the skin, followed by mucous membranes, deep connective tissue, and internal organs.…”

Section: Introductionmentioning

confidence: 99%

Very rare mediastinal location of Kaposiform haemangioendothelioma: A case report and a brief review of the previously published cases

Đuričić¹,

Sarajlija²,

Đokić³

et al. 2020

Scripta Medica

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Kaposiform haemangioendothelioma (KHE) is a rare, locally invasive vascular tumour that is commonly associated with the Kasabach-Merritt phenomenon (KMP). A case of a five-month-old female infant admitted for dyspnoea, stridor, and skin haematoma is presented. Computerised tomography of the chest showed a tumour mass occupying mediastinum and most of the left hemithorax, while laboratory analysis revealed a thrombocytopaenia and a consumption coagulopathy. Histology of tumour biopsy was characteristic of KHE with a component of tufted angioma. Corticosteroid treatment initially induced a reduction in tumour size, but progression occurred four weeks later and led to a fatal outcome despite additional chemotherapy. After a literature search, we found only 18 cases of mediastinal KHE published so far, with 21 % fatality rate. In the present case several risk factors for adverse outcome were present: onset of disease in early infancy, a large volume of the tumour, mediastinal location, KMP, and partial response to available therapy.

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Pediatric Soft-Tissue Tumors

Cited by 16 publications

References 56 publications

Precalcaneal congenital soft-tissue lesions in children: A case report of fibrous hamartoma of infancy and an approach to differential diagnosis

Precalcaneal congenital soft-tissue lesions in children: A case report of fibrous hamartoma of infancy and an approach to differential diagnosis

Pediatric Soft-Tissue Tumors and Pseudo-tumors: MR Imaging Features with Pathologic Correlation

Very rare mediastinal location of Kaposiform haemangioendothelioma: A case report and a brief review of the previously published cases

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