Pedicled Fat Pad Transfer for Prevention of Facial Depression After Excision of Soft-Tissue Masses

Kyung, Hyunwoo; Ahn, Chang Hwan; Lew, Dae Hyun; Song, Seung Han

doi:10.1097/dss.0000000000001979

2020

DOI: 10.1097/dss.0000000000001979

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Pedicled Fat Pad Transfer for Prevention of Facial Depression After Excision of Soft-Tissue Masses

Hyunwoo Kyung

Chang Hwan Ahn

Dae Hyun Lew

et al.

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Cited by 2 publications

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“…F acial depression malformation can be caused by congenital cranial dysplasia, facial atrophy, and aging, as well as local tissue defects due to infection, trauma, and tumor resection. As a relatively common technique in plastic and reconstructive surgery, volumetric change caused by atrophy and defects of soft tissues can be corrected by filling local depressions with autologous adipose tissue, [1][2][3] which has good biocompatibility and can be harvested from a wide range of sources. Grafting with autologous adipose tissue has recently become a common method for correction of soft tissue defects of the face.…”

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confidence: 99%

Study on the Application of Concentrated Growth Factor Combined With Adipose Transplantation in Repairing Depressed Deformities of Soft Tissue in the Face

Li,

Yang,

Lou

et al. 2023

Ann Plast Surg

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Background Autologous fat is a rich source of adipose tissue that is safe for transplantation. Decreasing the long-term absorption rate is key to improve the survival of transplanted adipose tissue. The aim of this study was to assess the effect of concentrated growth factor (CGF) on the survival of transplanted adipose tissue for repair of facial depression malformations. Methods Coleman adipose granules (CAGs) were prepared from venous blood. In the animal experiment, the ears of 30 healthy male New Zealand white rabbits were randomly allocated to 1 of 4 groups: CGF + CAG (CGF group), platelet-rich fibrin (PRF) + CAG (PRF group), CAG alone (CAG group), and adipose granule transplantation group (control group). Postoperative survival of the transplanted adipose tissue was assessed, the survival and absorption rates of adipose were calculated, and immunohistochemical analysis of specimens was conducted by staining with hematoxylin and eosin and Oil Red O. Of 43 outpatients, 22 received simple adipose transplantation and 21 received autologous CGF combined with adipose transplantation. The adipose absorption rate, complication rate, and cosmetic improvement of the 2 groups were compared. Results More adipocytes that are normal were observed in the CGF group, with fewer vacuoles and more uniform distribution of adipose tissue. Survival of the adipose tissue was superior in the CGF and PRF groups. Meanwhile, vascular density and long-term stability were better in the CGF group than the PRF group. In terms of clinical efficacy, the uniformity and survival rate of the adipose tissue were relatively improved in the CGF group compared with the simple adipose particle transplantation group, with less early liquefaction. Conclusion Concentrated growth factor stabilized and improved the survival of transplanted adipose tissue for filling of facial depression malformations.

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confidence: 99%

Study on the Application of Concentrated Growth Factor Combined With Adipose Transplantation in Repairing Depressed Deformities of Soft Tissue in the Face

Li,

Yang,

Lou

et al. 2023

Ann Plast Surg

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Commentary on Pedicled Fat Pad Used to Prevent Facial Depression After the Excision of a Soft Tissue Mass

Chesnut

2020

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Pedicled Fat Pad Transfer for Prevention of Facial Depression After Excision of Soft-Tissue Masses

Cited by 2 publications

References 4 publications

Study on the Application of Concentrated Growth Factor Combined With Adipose Transplantation in Repairing Depressed Deformities of Soft Tissue in the Face

Study on the Application of Concentrated Growth Factor Combined With Adipose Transplantation in Repairing Depressed Deformities of Soft Tissue in the Face

Commentary on Pedicled Fat Pad Used to Prevent Facial Depression After the Excision of a Soft Tissue Mass

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