PedsQL™ Cognitive Functioning Scale in youth with epilepsy: Reliability and validity

Varni, James W.; Junger, Katherine F.; Kellermann, Tanja S.; Grossman, Lauren Barrett; Wagner, Janelle L.; Mucci, Grace; Guilfoyle, Shanna M.; Smith, Gigi; Zupanc, Mary L.; Modi, Avani C.

doi:10.1016/j.yebeh.2019.106850

Cited by 12 publications

(11 citation statements)

References 48 publications

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“…Construct validity was tested to estimate the validity of our instrument by exploring the correlations of each item of the scale and the scores of depression. The correlation coe cient ranges from 0.682 to 0.888, which shows a large effect size (correlation coe cient ≥ 0.50) [19], indicating a good validity of our instrument. Cronbach's α of the scale was 0.965, indicating excellent internal consistency in this sample.…”

Section: Measurement Of Depressive Symptomsmentioning

confidence: 81%

“…For each domain of social capital, answers to the items were summated to obtain an overall score with higher scores indicating better social capital status. Construct validity was tested to estimate the validity of our instrument by exploring the correlations of each item of social capital dimension and the scores of social capital dimensions, respectively, where large effect size (correlation coe cient ≥ 0.50) was observed in all magnitude [19], indicating construct validity of our instrument. Internal consistency was calculated to prove the reliability of the measurement tool.…”

Section: Measurement Of Social Capitalmentioning

confidence: 99%

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Association between social capital and depression among older people: evidence from Anhui Province, China

Bai

et al. 2020

Preprint

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Background: To examine the relationship between social capital and depression among community-dwelling older adults in Anhui Province, China.Methods: A cross-sectional study was conducted among older people selected from three cities of Anhui Province, China using a multi-stage stratiﬁed cluster random sampling method. Data were collected through questionnaire interviews and information on demographic characteristics, social capital, and depression was collected. The generalized linear model and classification and regression tree model were employed to assess the association between social capital and depression. Results: Totally, 1,810 older people aged ≥ 60 years were included in the final analysis. Overall, all of the social capital dimensions were positively associated with depression: social participation (coefficient: 0.35, 95% CI: 0.22 - 0.48), social support (coefficient:0.18, 95% CI:0.07 - 0.28), social connection (coefficient: 0.76, 95% CI:0.53 - 1.00), trust (coefficient:0.62, 95% CI:0.33 - 0.92), cohesion (coefficient:0.31, 95% CI:0.17 - 0.44) and reciprocity (coefficient:0.30, 95% CI:0.11 - 0.48), which suggested that older people with higher social capital had a smaller chance to develop depression. A complex joint effect of certain social capital dimensions on depression was also observed. The association with depression and the combinative effect of social capital varied among older adults across the cities. Conclusions: Our study suggests that improving social capital could aid in the prevention of depression among older adults.

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Section: Measurement Of Depressive Symptomsmentioning

confidence: 81%

Section: Measurement Of Social Capitalmentioning

confidence: 99%

Association between social capital and depression among older people: evidence from Anhui Province, China

Bai

et al. 2020

Preprint

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“…The utilization of individual PedsQL Module scales has precedence from other PedsQL Modules. For example, the PedsQL Cognitive Functioning Scale has been used as a standalone scale, [36][37][38] originally embedded in the PedsQL Multidimensional Fatigue Scale. [39][40][41] It should be further noted that the PedsQL Multidimensional Fatigue Scale has also been integrated fully into the new PedsQL MS Module, including the General Fatigue Scale, Sleep/Rest Scale, and Cognitive Scale.…”

Section: Discussionmentioning

confidence: 99%

PedsQL Multiple Sclerosis Module Domain and Item Development: Qualitative Methods

Gaudioso

Mar

et al. 2021

J Child Neurol

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Background: The objective of this qualitative methods study was to develop the domains and items to support the content validity for the Pediatric Quality of Life Inventory (PedsQL) Multiple Sclerosis Module for youth with pediatric-onset multiple sclerosis. Methods: A literature review of multiple sclerosis–specific questionnaires and clinical research was conducted to generate domains. An expert panel composed of 12 neurologists who were pediatric-onset multiple sclerosis specialists provided feedback on the conceptual framework. Focus interviews with 9 youth with pediatric-onset multiple sclerosis and 6 parents were conducted to develop the relevant domains and item content from the patient and parent perspective. In the cognitive interviews phase, 9 youth with pediatric-onset multiple sclerosis and 6 parents provided feedback on item content, relevance, importance, and understandability of the pediatric-onset multiple sclerosis–specific domains and items. The final interview phase with 5 youth with pediatric-onset multiple sclerosis and 5 parents comprised a pilot testing of the new PedsQL MS Module. Results: Eighteen domains were derived from the qualitative methods with item content saturation achieved at 100 items based on 40 interviews with 23 youth with pediatric-onset multiple sclerosis aged 10-21 years and 17 parents. The domains derived include general fatigue, sleep/rest fatigue, cognitive functioning, tingling sensations, numbness sensations, physical weakness, pain, speech, balance, fine motor, vision, urination, constipation, bowel incontinence, worry, communication, treatment, and medicines. Conclusions: Qualitative methods involving 23 youth with pediatric-onset multiple sclerosis and 17 parents in the domain and item development process support the content validity for the new PedsQL MS Module. Future plans include a national field test of the PedsQL MS Module scales and items.

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“…Initially embedded within the PedsQL Multidimensional Fatigue Scale, 4,27‐30 the PedsQL Cognitive Functioning Scale has emerged as a standalone cognitive functioning measure in pediatric populations with known or suspected impairments in cognitive functioning 31‐34 . The PedsQL Cognitive Functioning Scale has been shown to be significantly correlated with the original 72‐item Behavior Rating Inventory of Executive Function (BRIEF), 31,34,35 a widely validated measure of executive functioning 36,37 . The PedsQL Cognitive Functioning Scale has demonstrated medium to large effect size correlations with the BRIEF summary and subscales scores, suggesting that it may be measuring important facets of executive functioning 31,34,35 .…”

Section: Methodsmentioning

confidence: 99%

“…The PedsQL Cognitive Functioning Scale has been shown to be significantly correlated with the original 72‐item Behavior Rating Inventory of Executive Function (BRIEF), 31,34,35 a widely validated measure of executive functioning 36,37 . The PedsQL Cognitive Functioning Scale has demonstrated medium to large effect size correlations with the BRIEF summary and subscales scores, suggesting that it may be measuring important facets of executive functioning 31,34,35 . The format, instructions, Likert scale, and scoring method are identical to the PedsQL 4.0 Generic Core Scales, with higher scores indicating better HRQOL (fewer cognitive problems).…”

Section: Methodsmentioning

confidence: 99%

Cognitive functioning, patient health communication, and worry mediate pain predictive effects on health‐related quality of life in youth with sickle cell disease

Varni¹

2020

Pediatric Blood & Cancer

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Objectives: The objective was to investigate the serial mediating effects of perceived cognitive functioning, patient health communication, and disease-specific worry in the relationship between pain and overall generic health-related quality of life (HRQOL) in youth with sickle cell disease (SCD) from the patient perspective. Methods: The pain, cognitive functioning, communication and worry scales from the Pediatric Quality of Life Inventory (PedsQL) Sickle Cell Disease Module and the Ped-sQL Multidimensional Fatigue Scale, and the PedsQL 4.0 Generic Core Scales were completed in a multisite national study by 233 youth with SCD of ages 5-18. Hierarchical multiple regression and serial multiple mediator model analyses were conducted to test the mediating effects of perceived cognitive functioning, health communication, and disease-specific worry as intervening variables in the association between the pain predictor variable and overall generic HRQOL. Results: Pain predictive effects on overall generic HRQOL were serially mediated by cognitive functioning, health communication, and disease-specific worry. In predictive analytics models utilizing hierarchical multiple regression analyses with age and gender demographic covariates, pain, cognitive functioning, health communication, and worry accounted for 65% of the variance in patient-reported overall generic HRQOL (P < .001), representing a large effect size. Conclusions: Perceived cognitive functioning, patient health communication, and disease-specific worry explain in part the mechanism of pain predictive effects on overall generic HRQOL in youth with SCD. Identifying SCD-specific pain, perceived cognitive functioning, health communication, and disease-specific worry as predictor variables of overall generic HRQOL from the patient perspective may inform clinical interventions and future patient-centered clinical research.

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PedsQL™ Cognitive Functioning Scale in youth with epilepsy: Reliability and validity

Cited by 12 publications

References 48 publications

Association between social capital and depression among older people: evidence from Anhui Province, China

Association between social capital and depression among older people: evidence from Anhui Province, China

PedsQL Multiple Sclerosis Module Domain and Item Development: Qualitative Methods

Cognitive functioning, patient health communication, and worry mediate pain predictive effects on health‐related quality of life in youth with sickle cell disease

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