Pedunculated Hepatic Hemangiomas often Misdiagnosed Despite Their Typical Findings

Ha, Chi

doi:10.2174/1874300501307010001

Cited by 12 publications

(28 citation statements)

References 24 publications

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“…Hemangioma is the most common benign liver tumor (1-8) , with a prevalence of 0.4-20% in necropsies (1,5-8) . In most cases, hemangiomas are small, asymptomatic and incidentally found at imaging studies (1,2,5,6) .…”

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confidence: 99%

“…In most cases, hemangiomas are small, asymptomatic and incidentally found at imaging studies (1,2,5,6) .…”

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confidence: 99%

“…In spite of the lack of consensus about the dimensions to define a giant hemangioma, ranging from 4 to 10 cm according to the literature, it is known that the exophytic presentation, particularly those pedunculated, are very rare (1-3,5,6) . The first case was reported by Ellis et al in 1985; and up to 2013, only 24 cases were described in the literature (1,4) .…”

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confidence: 99%

“…The first case was reported by Ellis et al in 1985; and up to 2013, only 24 cases were described in the literature (1,4) .…”

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confidence: 99%

“…In almost 50% of cases, pedunculated hemangiomas are symptomatic at the diagnosis (1) and, likely any giant lesion, may determine compression of the intrahepatic biliary ducts, vascular structures or adjacent organs, manifesting with pain, early satiety, hemorrhage, jaundice, nausea and vomiting (1,2,5,6,8) . Main complications include torsion due to a long and mobile pedicle, infarction (5,6) , spontaneous or traumatic rupture, congestive heart failure, and Kasabach-Merritt syndrome (2,6,7) .…”

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confidence: 99%

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Giant pedunculated hemangioma of the liver

et al. 2016

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confidence: 99%

“…In most cases, hemangiomas are small, asymptomatic and incidentally found at imaging studies (1,2,5,6) .…”

mentioning

confidence: 99%

mentioning

confidence: 99%

“…The first case was reported by Ellis et al in 1985; and up to 2013, only 24 cases were described in the literature (1,4) .…”

mentioning

confidence: 99%

mentioning

confidence: 99%

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Giant pedunculated hemangioma of the liver

et al. 2016

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Giant pedunculated hepatic hemangioma accompanied by a 10‐year history of taking oral contraceptive: A case report and literature review

Samidoust,

Moayerifar,

Mohammadian

et al. 2024

Clinical Case Reports

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Key Clinical MessageGiant pedunculated hepatic hemangiomas, mostly seen in women, are considered a rare type of giant hepatic hemangioma, with challenging diagnosis. Unlike other types of liver hemangiomas, they can manifest different kinds of symptoms, and are prone to life‐threatening manifestations like rupture or torsion.AbstractHemangioma is the most common benign liver primary tumor. Hepatic hemangioma >4 cm (some studies suggest >10 cm) is referred to as a giant hemangioma. Although hepatic hemangioma does not manifest symptoms in most cases, a giant hepatic hemangioma can manifest different kinds of symptoms. Giant pedunculated hepatic hemangiomas are considered a rare type of giant hepatic hemangioma, with challenging diagnosis, as the thin pedicle could be hard to be detected on imaging. A 41‐year‐old woman was admitted to our hospital, with dull discomfort of the right upper quadrant and epigastric region and early satiety for the past 7 months, with the history of taking oral contraceptive (OCP) for 10 years. Ultrasound and computed tomography revealed a 130 × 124 × 76 mm solid mass, with central cystic lesion, located in the midline of the epigastric region, attaching to the inferior surface of the third segment of the left lobe of the liver. Due to the potential risk for torsion, and rupture of the hemangioma, the management of the patient proceeded to surgical excision. Pathological examination of the specimen confirmed the diagnosis of hepatic hemangioma. Giant pedunculated hepatic hemangioma is a rare benign tumor. It demonstrates higher incidence rate in women, as some hemangiomas have estrogen receptors, and estrogen can lead to endothelial cell proliferation and organization in vascular structure. Most hemangiomas do not express any symptoms; therefore, no treatment is needed except for the patients who manifest symptoms, or in giant pedunculated hemangiomas, as they are prone to rupture or torsion. In this review most cases were female, and most of them presented with abdominal pain, in most cases the tumor located in the left lobe of the liver. Almost all the reviewed cases underwent surgery. Giant hepatic hemangioma is a differential diagnosis of palpable mass, or other symptoms of the right upper quadrant, and epigastric region specially in women taking OCP. Imaging is needed to rule out these tumors, and most often, pedunculated hemangioma is harder to be defined on imaging. It requires surgery because of the risk of acute problems, such as torsion and rupture.

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Imaging Techniques, Normal Post-procedural Findings and Complications After Upper Gastrointestinal Endoscopy

Tonolini

2016

Imaging Complications of Gastrointestinal and Biliopancreatic Endoscopy Procedures

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Pedunculated Hepatic Hemangiomas often Misdiagnosed Despite Their Typical Findings

Cited by 12 publications

References 24 publications

Giant pedunculated hemangioma of the liver

Giant pedunculated hemangioma of the liver

Giant pedunculated hepatic hemangioma accompanied by a 10‐year history of taking oral contraceptive: A case report and literature review

Imaging Techniques, Normal Post-procedural Findings and Complications After Upper Gastrointestinal Endoscopy

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